Quantitative Compression Elastography With an Uncalibrated Stress Sensor

Tissue stiffness is a key biomechanical property that can be exploited for diagnostic and therapeutic purposes. Tissue stiffness is typically measured quantitatively via shear wave elastography or qualitatively through compressive strain elastography. This work focuses on merging the two by implemen...

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Main Authors: Justin R. Rippy, Manmohan Singh, Achuth Nair, Salavat Aglyamov, Kirill V. Larin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.917842/full
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author Justin R. Rippy
Manmohan Singh
Achuth Nair
Salavat Aglyamov
Kirill V. Larin
Kirill V. Larin
author_facet Justin R. Rippy
Manmohan Singh
Achuth Nair
Salavat Aglyamov
Kirill V. Larin
Kirill V. Larin
author_sort Justin R. Rippy
collection DOAJ
description Tissue stiffness is a key biomechanical property that can be exploited for diagnostic and therapeutic purposes. Tissue stiffness is typically measured quantitatively via shear wave elastography or qualitatively through compressive strain elastography. This work focuses on merging the two by implementing an uncalibrated stress sensor to allow for the calculation of Young’s modulus during compression elastography. Our results show that quantitative compression elastography is able to measure Young’s modulus values in gelatin and tissue samples that agree well with uniaxial compression testing.
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spelling doaj.art-0cb6815217c548658c6ef1b283b078912022-12-22T02:32:37ZengFrontiers Media S.A.Frontiers in Physics2296-424X2022-06-011010.3389/fphy.2022.917842917842Quantitative Compression Elastography With an Uncalibrated Stress SensorJustin R. Rippy0Manmohan Singh1Achuth Nair2Salavat Aglyamov3Kirill V. Larin4Kirill V. Larin5Biomedical Optics Laboratory, Department of Biomedical Engineering, University of Houston, Houston, TX, United StatesBiomedical Optics Laboratory, Department of Biomedical Engineering, University of Houston, Houston, TX, United StatesBiomedical Optics Laboratory, Department of Biomedical Engineering, University of Houston, Houston, TX, United StatesBiomedical Optics Laboratory, Department of Mechanical Engineering, University of Houston, Houston, TX, United StatesBiomedical Optics Laboratory, Department of Biomedical Engineering, University of Houston, Houston, TX, United StatesBaylor College of Medicine, Molecular Physiology and Biophysics, Houston, TX, United StatesTissue stiffness is a key biomechanical property that can be exploited for diagnostic and therapeutic purposes. Tissue stiffness is typically measured quantitatively via shear wave elastography or qualitatively through compressive strain elastography. This work focuses on merging the two by implementing an uncalibrated stress sensor to allow for the calculation of Young’s modulus during compression elastography. Our results show that quantitative compression elastography is able to measure Young’s modulus values in gelatin and tissue samples that agree well with uniaxial compression testing.https://www.frontiersin.org/articles/10.3389/fphy.2022.917842/fullultrasound elastographycompressionsensorexcitationshear wavequantitative compression elastography
spellingShingle Justin R. Rippy
Manmohan Singh
Achuth Nair
Salavat Aglyamov
Kirill V. Larin
Kirill V. Larin
Quantitative Compression Elastography With an Uncalibrated Stress Sensor
Frontiers in Physics
ultrasound elastography
compression
sensor
excitation
shear wave
quantitative compression elastography
title Quantitative Compression Elastography With an Uncalibrated Stress Sensor
title_full Quantitative Compression Elastography With an Uncalibrated Stress Sensor
title_fullStr Quantitative Compression Elastography With an Uncalibrated Stress Sensor
title_full_unstemmed Quantitative Compression Elastography With an Uncalibrated Stress Sensor
title_short Quantitative Compression Elastography With an Uncalibrated Stress Sensor
title_sort quantitative compression elastography with an uncalibrated stress sensor
topic ultrasound elastography
compression
sensor
excitation
shear wave
quantitative compression elastography
url https://www.frontiersin.org/articles/10.3389/fphy.2022.917842/full
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AT kirillvlarin quantitativecompressionelastographywithanuncalibratedstresssensor
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