Advantages and pitfalls of clinical application of sugammadex
Sugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium. Its introduction has revolutionized anesthesia practice because it is a safe, predictable, and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Anesthesiologists
2020-07-01
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| Series: | Anesthesia and Pain Medicine |
| Subjects: | |
| Online Access: | http://www.anesth-pain-med.org/upload/pdf/apm-19099.pdf |
| _version_ | 1797825434647265280 |
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| author | Hyung Young Lee Ki Tae Jung |
| author_facet | Hyung Young Lee Ki Tae Jung |
| author_sort | Hyung Young Lee |
| collection | DOAJ |
| description | Sugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium. Its introduction has revolutionized anesthesia practice because it is a safe, predictable, and reliable neuromuscular antagonist. Hence, its use has increased worldwide. Further, it has been in the spotlight for recovering from deep NMB in laparoscopic surgery and improving the surgical condition. Recently, studies have been conducted on the postoperative outcome after deep NMB and use of sugammadex in various clinical conditions. However, with increase in sugammadex use, reports regarding its complications are increasing. Appropriate dosing of sugammadex with quantitative neuromuscular monitoring is emphasized because under-dosing or over-dosing of sugammadex might be associated with unexperienced complications. Sugammadex is now leaping into an ideal reversal agent, changing the anesthesia practice. |
| first_indexed | 2024-03-13T10:53:57Z |
| format | Article |
| id | doaj.art-0cb7333bc17940e29a5d3e6a2f9b420e |
| institution | Directory Open Access Journal |
| issn | 1975-5171 2383-7977 |
| language | English |
| last_indexed | 2024-03-13T10:53:57Z |
| publishDate | 2020-07-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Anesthesia and Pain Medicine |
| spelling | doaj.art-0cb7333bc17940e29a5d3e6a2f9b420e2023-05-17T05:41:38ZengKorean Society of AnesthesiologistsAnesthesia and Pain Medicine1975-51712383-79772020-07-0115325926810.17085/apm.190991024Advantages and pitfalls of clinical application of sugammadexHyung Young Lee0Ki Tae Jung1 Department of Anesthesiology and Pain Medicine, Chosun University Hospital, School of Medicine, Chosun University, Gwangju, Korea Department of Anesthesiology and Pain Medicine, Chosun University Hospital, School of Medicine, Chosun University, Gwangju, KoreaSugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium. Its introduction has revolutionized anesthesia practice because it is a safe, predictable, and reliable neuromuscular antagonist. Hence, its use has increased worldwide. Further, it has been in the spotlight for recovering from deep NMB in laparoscopic surgery and improving the surgical condition. Recently, studies have been conducted on the postoperative outcome after deep NMB and use of sugammadex in various clinical conditions. However, with increase in sugammadex use, reports regarding its complications are increasing. Appropriate dosing of sugammadex with quantitative neuromuscular monitoring is emphasized because under-dosing or over-dosing of sugammadex might be associated with unexperienced complications. Sugammadex is now leaping into an ideal reversal agent, changing the anesthesia practice.http://www.anesth-pain-med.org/upload/pdf/apm-19099.pdfcomplicationsneuromuscular blockadereviewrocuroniumsugammadex |
| spellingShingle | Hyung Young Lee Ki Tae Jung Advantages and pitfalls of clinical application of sugammadex Anesthesia and Pain Medicine complications neuromuscular blockade review rocuronium sugammadex |
| title | Advantages and pitfalls of clinical application of sugammadex |
| title_full | Advantages and pitfalls of clinical application of sugammadex |
| title_fullStr | Advantages and pitfalls of clinical application of sugammadex |
| title_full_unstemmed | Advantages and pitfalls of clinical application of sugammadex |
| title_short | Advantages and pitfalls of clinical application of sugammadex |
| title_sort | advantages and pitfalls of clinical application of sugammadex |
| topic | complications neuromuscular blockade review rocuronium sugammadex |
| url | http://www.anesth-pain-med.org/upload/pdf/apm-19099.pdf |
| work_keys_str_mv | AT hyungyounglee advantagesandpitfallsofclinicalapplicationofsugammadex AT kitaejung advantagesandpitfallsofclinicalapplicationofsugammadex |