Cardiovascular Safety of Febuxostat and Allopurinol in Hyperuricemic Patients With or Without Gout: A Network Meta-Analysis

Cardiovascular Safety of Febuxostat and Allopurinol in Hyperuricemic Patients With or Without Gout: A Network Meta-Analysis

Background: Hyperuricemia is a common metabolic disease and has become a public health problem because of its increasing prevalence and association with comorbidities. Allopurinol and febuxostat are recommended as the first-line treatments for hyperuricemia and gout. But cardiovascular safety betwee...

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Bibliographic Details
Main Authors: Shengzhao Zhang, Ting Xu, Qingyang Shi, Sheyu Li, Ling Wang, Zhenmei An, Na Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
febuxostat
allopurinol
hyperuricemia
network meta-analysis
cardiovascular safety
Bayesian framework
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.698437/full

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