Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer
<p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.</p> <p>Methods</p> <p>From December 6, 2006 through O...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-01-01
|
| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/11/37 |
| _version_ | 1828533202103304192 |
|---|---|
| author | Chen Yu-Jen Lin Yu-Chin Wu Le-Jung Lin Shih-Chiang Hu Kawang-Yu Liao Li-Jen Kuo Ying-Shiung Hsieh Chen-Hsi Wang Li-Ying Hsieh Yen-Ping Lin Shoei Chen Chun-Yi Chen Chien-An Shueng Pei-Wei |
| author_facet | Chen Yu-Jen Lin Yu-Chin Wu Le-Jung Lin Shih-Chiang Hu Kawang-Yu Liao Li-Jen Kuo Ying-Shiung Hsieh Chen-Hsi Wang Li-Ying Hsieh Yen-Ping Lin Shoei Chen Chun-Yi Chen Chien-An Shueng Pei-Wei |
| author_sort | Chen Yu-Jen |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.</p> <p>Methods</p> <p>From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.</p> <p>Results</p> <p>The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation ≤ 6 wk, and the overall treatment time of radiation ≤ 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.</p> <p>Conclusions</p> <p>HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings.</p> |
| first_indexed | 2024-12-11T23:05:42Z |
| format | Article |
| id | doaj.art-0cbf5c026eed409983098e6c42c8dfaf |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-11T23:05:42Z |
| publishDate | 2011-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-0cbf5c026eed409983098e6c42c8dfaf2022-12-22T00:46:55ZengBMCBMC Cancer1471-24072011-01-011113710.1186/1471-2407-11-37Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancerChen Yu-JenLin Yu-ChinWu Le-JungLin Shih-ChiangHu Kawang-YuLiao Li-JenKuo Ying-ShiungHsieh Chen-HsiWang Li-YingHsieh Yen-PingLin ShoeiChen Chun-YiChen Chien-AnShueng Pei-Wei<p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.</p> <p>Methods</p> <p>From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.</p> <p>Results</p> <p>The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation ≤ 6 wk, and the overall treatment time of radiation ≤ 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.</p> <p>Conclusions</p> <p>HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings.</p>http://www.biomedcentral.com/1471-2407/11/37 |
| spellingShingle | Chen Yu-Jen Lin Yu-Chin Wu Le-Jung Lin Shih-Chiang Hu Kawang-Yu Liao Li-Jen Kuo Ying-Shiung Hsieh Chen-Hsi Wang Li-Ying Hsieh Yen-Ping Lin Shoei Chen Chun-Yi Chen Chien-An Shueng Pei-Wei Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer BMC Cancer |
| title | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
| title_full | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
| title_fullStr | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
| title_full_unstemmed | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
| title_short | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
| title_sort | image guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high risk oral cavity cancer |
| url | http://www.biomedcentral.com/1471-2407/11/37 |
| work_keys_str_mv | AT chenyujen imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT linyuchin imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT wulejung imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT linshihchiang imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT hukawangyu imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT liaolijen imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT kuoyingshiung imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT hsiehchenhsi imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT wangliying imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT hsiehyenping imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT linshoei imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT chenchunyi imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT chenchienan imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer AT shuengpeiwei imageguidedintensitymodulatedradiotherapywithhelicaltomotherapyforpostoperativetreatmentofhighriskoralcavitycancer |