The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography
Aim: The study aimed to evaluate the normal liver stiffness value (LSV) with shear wave elastography (SWE) in children and adults, and reveal the relationship between LSV and age, gender, body mass index (BMI), and liver size. Material and Methods: A total of 173 healthy volunteers, 92 female and 81...
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| Format: | Article |
| Language: | English |
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Duzce University
2022-08-01
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| Series: | Düzce Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/2374639 |
| _version_ | 1797668814247165952 |
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| author | Osman Demir Meral Gizem Akbaş Ergün Sönmezgöz Eda Albayrak |
| author_facet | Osman Demir Meral Gizem Akbaş Ergün Sönmezgöz Eda Albayrak |
| author_sort | Osman Demir |
| collection | DOAJ |
| description | Aim: The study aimed to evaluate the normal liver stiffness value (LSV) with shear wave elastography (SWE) in children and adults, and reveal the relationship between LSV and age, gender, body mass index (BMI), and liver size.
Material and Methods: A total of 173 healthy volunteers, 92 female and 81 male, aged between 4 and 50 years were included in this study. LSV measurements were performed in the supine position during normal breathing and from the right intercostal space where the acoustic window is best. The mean of the five valid measurements was accepted as the mean LSV. The relationship between the mean LSV and age, gender, liver size, and BMI was evaluated.
Results: There was a moderate positive correlation between LSV and age (p<0.001, r=0.609), LSV and BMI (p<0.001, r=0.512), and LSV and liver size (p<0.001, r=0.485). However, the multivariate linear regression analysis revealed that the effects of liver size and gender on LSV were not significant (p=0.091, and p=0.759, respectively), while the effects of age and BMI were significant (p<0.001, and p=0.019, respectively).
Conclusion: 2-D SWE is an effective imaging method to evaluate LSV both in children and adults. LSV increases with increasing age and BMI, however, it is not affected by gender and liver size. The normal LSV obtained in the present study can be used as reference values in the evaluation of various liver diseases with 2-D SWE. |
| first_indexed | 2024-03-11T20:34:57Z |
| format | Article |
| id | doaj.art-0cbf987a5979409b87fda22428181652 |
| institution | Directory Open Access Journal |
| issn | 1307-671X |
| language | English |
| last_indexed | 2024-03-11T20:34:57Z |
| publishDate | 2022-08-01 |
| publisher | Duzce University |
| record_format | Article |
| series | Düzce Tıp Fakültesi Dergisi |
| spelling | doaj.art-0cbf987a5979409b87fda224281816522023-10-02T06:46:06ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2022-08-0124215716110.18678/dtfd.110355997The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave ElastographyOsman Demir0Meral Gizem Akbaş1Ergün Sönmezgöz2Eda Albayrak3TOKAT GAZİOSMANPAŞA ÜNİVERSİTESİ, TIP FAKÜLTESİTOKAT GAZİOSMANPAŞA ÜNİVERSİTESİ, TIP FAKÜLTESİTOKAT GAZİOSMANPAŞA ÜNİVERSİTESİ, TIP FAKÜLTESİTOKAT GAZİOSMANPAŞA ÜNİVERSİTESİ, TIP FAKÜLTESİAim: The study aimed to evaluate the normal liver stiffness value (LSV) with shear wave elastography (SWE) in children and adults, and reveal the relationship between LSV and age, gender, body mass index (BMI), and liver size. Material and Methods: A total of 173 healthy volunteers, 92 female and 81 male, aged between 4 and 50 years were included in this study. LSV measurements were performed in the supine position during normal breathing and from the right intercostal space where the acoustic window is best. The mean of the five valid measurements was accepted as the mean LSV. The relationship between the mean LSV and age, gender, liver size, and BMI was evaluated. Results: There was a moderate positive correlation between LSV and age (p<0.001, r=0.609), LSV and BMI (p<0.001, r=0.512), and LSV and liver size (p<0.001, r=0.485). However, the multivariate linear regression analysis revealed that the effects of liver size and gender on LSV were not significant (p=0.091, and p=0.759, respectively), while the effects of age and BMI were significant (p<0.001, and p=0.019, respectively). Conclusion: 2-D SWE is an effective imaging method to evaluate LSV both in children and adults. LSV increases with increasing age and BMI, however, it is not affected by gender and liver size. The normal LSV obtained in the present study can be used as reference values in the evaluation of various liver diseases with 2-D SWE.https://dergipark.org.tr/en/download/article-file/2374639: livershear wave elastographyultrasonographykaraciğer;elastografiultrasonografi |
| spellingShingle | Osman Demir Meral Gizem Akbaş Ergün Sönmezgöz Eda Albayrak The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography Düzce Tıp Fakültesi Dergisi : liver shear wave elastography ultrasonography karaciğer; elastografi ultrasonografi |
| title | The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography |
| title_full | The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography |
| title_fullStr | The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography |
| title_full_unstemmed | The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography |
| title_short | The Relationship of Liver Stiffness with Liver Size, Age, Gender, and Body Mass Index in Child and Adult Age Groups by 2-D Shear Wave Elastography |
| title_sort | relationship of liver stiffness with liver size age gender and body mass index in child and adult age groups by 2 d shear wave elastography |
| topic | : liver shear wave elastography ultrasonography karaciğer; elastografi ultrasonografi |
| url | https://dergipark.org.tr/en/download/article-file/2374639 |
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