rare cause of recurrent haemolytic anaemia: carboplatin and paclitaxel-induced autoimmune haemolytic anaemia

Drug-induced immune haemolytic anaemia (DIIHA) is a rare but serious complication affecting approximately 1 in 1,000,000 patients, but its incidence might be underestimated due to misdiagnosis. Several factors should be considered to ensure an accurate diagnosis, including previous medical history,...

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Bibliographic Details
Main Authors: Pitchaporn Yingchoncharoen, Jerapas Thongpiya, Shrinkhala Maharjan, Mahmoud Abdelnabi, Samuel Kim, Sakditad Saowapa, Judy Lalmuanpuii
Format: Article
Language:English
Published: SMC MEDIA SRL 2023-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://ejcrim.com/index.php/EJCRIM/article/view/3740
Description
Summary:Drug-induced immune haemolytic anaemia (DIIHA) is a rare but serious complication affecting approximately 1 in 1,000,000 patients, but its incidence might be underestimated due to misdiagnosis. Several factors should be considered to ensure an accurate diagnosis, including previous medical history, comorbidities, drug history, the temporal relationship between drug exposure and symptom onset, haemolytic features, and comorbidities in suspected cases. The authors report a case of DIIHA caused by combination chemotherapy with carboplatin and paclitaxel complicated with haeme pigment- induced acute kidney injury.
ISSN:2284-2594