Bone marrow granulomatosis: two case reports

Bone marrow granulomatosis is not a common finding and remains a diagnostic challenge. Here below we report two bizarre but not so rare cases of bone marrow granulomatosis: bone marrow involvement by M. avium-intracellulare and reaction to intravesical administration of bacille of Calmette-Guèrin fo...

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Main Authors: Giacomo Andreani, Alessandro Morotti, Matteo Dragani, Francesca Caciolli, Bruna Crea, Valerio Marci, Ubaldo Familiari, Angelo Guerrasio
Format: Article
Language:English
Published: PAGEPress Publications 2019-06-01
Series:Italian Journal of Medicine
Subjects:
Online Access:https://italjmed.org/index.php/ijm/article/view/1150
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author Giacomo Andreani
Alessandro Morotti
Matteo Dragani
Francesca Caciolli
Bruna Crea
Valerio Marci
Ubaldo Familiari
Angelo Guerrasio
author_facet Giacomo Andreani
Alessandro Morotti
Matteo Dragani
Francesca Caciolli
Bruna Crea
Valerio Marci
Ubaldo Familiari
Angelo Guerrasio
author_sort Giacomo Andreani
collection DOAJ
description Bone marrow granulomatosis is not a common finding and remains a diagnostic challenge. Here below we report two bizarre but not so rare cases of bone marrow granulomatosis: bone marrow involvement by M. avium-intracellulare and reaction to intravesical administration of bacille of Calmette-Guèrin for non-muscle-invasive bladder cancer; two distinct culprits suggesting the wide range of possible causative factors of this histopathological pattern. In the discussion we provide a brief overview of causes and suggestions for a diagnostic approach.
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spelling doaj.art-0cc1f7b298364db5b4a178ae9544c7a22023-12-02T17:06:20ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522019-06-011210.4081/itjm.2019.1150Bone marrow granulomatosis: two case reportsGiacomo Andreani0Alessandro Morotti1Matteo Dragani2Francesca Caciolli3Bruna Crea4Valerio Marci5Ubaldo Familiari6Angelo Guerrasio7Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Pathology, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Pathology, San Luigi Gonzaga Hospital, Orbassano (TO)Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Orbassano (TO)Bone marrow granulomatosis is not a common finding and remains a diagnostic challenge. Here below we report two bizarre but not so rare cases of bone marrow granulomatosis: bone marrow involvement by M. avium-intracellulare and reaction to intravesical administration of bacille of Calmette-Guèrin for non-muscle-invasive bladder cancer; two distinct culprits suggesting the wide range of possible causative factors of this histopathological pattern. In the discussion we provide a brief overview of causes and suggestions for a diagnostic approach.https://italjmed.org/index.php/ijm/article/view/1150Bacille of Calmette-Guèrinbone marrow granulomatosismycobacteriametallosispancytopenia.
spellingShingle Giacomo Andreani
Alessandro Morotti
Matteo Dragani
Francesca Caciolli
Bruna Crea
Valerio Marci
Ubaldo Familiari
Angelo Guerrasio
Bone marrow granulomatosis: two case reports
Italian Journal of Medicine
Bacille of Calmette-Guèrin
bone marrow granulomatosis
mycobacteria
metallosis
pancytopenia.
title Bone marrow granulomatosis: two case reports
title_full Bone marrow granulomatosis: two case reports
title_fullStr Bone marrow granulomatosis: two case reports
title_full_unstemmed Bone marrow granulomatosis: two case reports
title_short Bone marrow granulomatosis: two case reports
title_sort bone marrow granulomatosis two case reports
topic Bacille of Calmette-Guèrin
bone marrow granulomatosis
mycobacteria
metallosis
pancytopenia.
url https://italjmed.org/index.php/ijm/article/view/1150
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