Genetic characterization and molecular evolution of type 3 vaccine-derived polioviruses from an immunodeficient patient in China

Genetic characterization and molecular evolution of type 3 vaccine-derived polioviruses from an immunodeficient patient in China

Summary: In 2013, a case of immunodeficiency vaccine-derived poliovirus (iVDPV) was identified in Jiangxi Province, China. In this study, we purified 14 type 3 original viral isolates from this case and characterized the molecular evolution of these iVDPVs for 298 days. Genetic variants were found i...

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Bibliographic Details
Main Authors: Qin Guo, Shuangli Zhu, Dongyan Wang, Xiaolei Li, Hui Zhu, Yang Song, Xiaoqing Liu, Fang Xiao, Hehe Zhao, Huanhuan Lu, Jinbo Xiao, Liheng Yu, Wenhui Wang, Yun He, Ying Liu, Jichen Li, Yong Zhang, Wenbo Xu, Dongmei Yan
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Virus Research
Subjects:
Poliovirus
Immunodeficiency
Oral poliovirus vaccine
Genetic characterization
Molecular evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223001399

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