The prevalence of the ABCB1-1Δ variant in a clinical veterinary setting: The risk of not genotyping.

Multidrug sensitivity is an autosomal recessive disorder in dogs caused by a 4-bp deletion in the ABCB1 gene, often referred to as the ABCB1-1Δ variant. This disease has a high prevalence in some breeds and causes adverse reactions to certain drugs when given in normal doses. Though most dogs known...

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Bibliographic Details
Main Authors: Evy Beckers, Iris Casselman, Emma Soudant, Sylvie Daminet, Dominique Paepe, Luc Peelman, Bart J G Broeckx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273706