Alzheimer’s Disease-Related Genes Identified by Linking Spatial Patterns of Pathology and Gene Expression

Alzheimer’s Disease-Related Genes Identified by Linking Spatial Patterns of Pathology and Gene Expression

BackgroundAlzheimer’s Disease (AD) is an age-related neurodegenerative disease with a poorly understood etiology, shown to be partly genetic. Glucose hypometabolism, extracellular Amyloid-beta (Aβ) deposition, and intracellular Tau deposition are cardinal features of AD and display characteristic sp...

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Bibliographic Details
Main Authors: Roger Mullins, Dimitrios Kapogiannis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
tau
FDG-18
PLS-DA
ADNI
allen human brain atlas
Alzheimer’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.908650/full

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