High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma

Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare subtype of renal cell carcinoma. Although usually indolent, high-grade MTSCC has been reported to exhibit an aggressive clinical course. Herein, we report a case of high-grade renal MTSCC. An 86-year-old man visited our hospital with feve...

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Main Authors: Kyotaro Fukuta, Ryoichi Nakanishi, Takahiro Moriyama, Hirofumi Izaki, Takumi Kakimoto, Takeshi Oya, Tomoya Fukawa, Kunihisa Yamaguchi, Yasuyo Yamamoto, Masayuki Takahashi, Yasushi Sutou, Hiro-omi Kanayama
Format: Article
Language:English
Published: Karger Publishers 2022-05-01
Series:Case Reports in Oncology
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Online Access:https://www.karger.com/Article/FullText/524897
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author Kyotaro Fukuta
Ryoichi Nakanishi
Takahiro Moriyama
Hirofumi Izaki
Takumi Kakimoto
Takeshi Oya
Tomoya Fukawa
Kunihisa Yamaguchi
Yasuyo Yamamoto
Masayuki Takahashi
Yasushi Sutou
Hiro-omi Kanayama
author_facet Kyotaro Fukuta
Ryoichi Nakanishi
Takahiro Moriyama
Hirofumi Izaki
Takumi Kakimoto
Takeshi Oya
Tomoya Fukawa
Kunihisa Yamaguchi
Yasuyo Yamamoto
Masayuki Takahashi
Yasushi Sutou
Hiro-omi Kanayama
author_sort Kyotaro Fukuta
collection DOAJ
description Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare subtype of renal cell carcinoma. Although usually indolent, high-grade MTSCC has been reported to exhibit an aggressive clinical course. Herein, we report a case of high-grade renal MTSCC. An 86-year-old man visited our hospital with fever and fatigue. Based on contrast-enhanced computed tomography findings, the patient was diagnosed with clinical stage T2aN0M0 right renal cell carcinoma and underwent laparoscopic radical nephrectomy. Histological examination showed tubular to tubulopapillary structures accompanied by mucinous stroma, suggesting high-grade renal MTSCC. He remained recurrence- and metastasis-free 6 months after nephrectomy. Since high-grade renal MTSCC may have an aggressive clinical course, such patients should be observed carefully after radical nephrectomy.
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spelling doaj.art-0cccb030019f418c997e7565ed36c1c12022-12-22T00:58:53ZengKarger PublishersCase Reports in Oncology1662-65752022-05-0115258058510.1159/000524897524897High-Grade Renal Mucinous Tubular and Spindle Cell CarcinomaKyotaro Fukuta0Ryoichi Nakanishi1Takahiro Moriyama2Hirofumi Izaki3Takumi Kakimoto4Takeshi Oya5Tomoya Fukawa6Kunihisa Yamaguchi7Yasuyo Yamamoto8Masayuki Takahashi9https://orcid.org/0000-0003-2449-3148Yasushi Sutou10Hiro-omi Kanayama11Department of Urology, Tsurugi Municipal Handa Hospital, Tsurugi, JapanDepartment of Urology, Tokushima Prefectural Miyoshi Hospital, Miyoshi, JapanDepartment of Urology, Tsurugi Municipal Handa Hospital, Tsurugi, JapanDepartment of Urology, Tokushima Prefectural Central Hospital, Tokushima, JapanDepartment of Pathology and Laboratory Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanDepartment of Urology, Tsurugi Municipal Handa Hospital, Tsurugi, JapanDepartment of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, JapanMucinous tubular and spindle cell carcinoma (MTSCC) is a rare subtype of renal cell carcinoma. Although usually indolent, high-grade MTSCC has been reported to exhibit an aggressive clinical course. Herein, we report a case of high-grade renal MTSCC. An 86-year-old man visited our hospital with fever and fatigue. Based on contrast-enhanced computed tomography findings, the patient was diagnosed with clinical stage T2aN0M0 right renal cell carcinoma and underwent laparoscopic radical nephrectomy. Histological examination showed tubular to tubulopapillary structures accompanied by mucinous stroma, suggesting high-grade renal MTSCC. He remained recurrence- and metastasis-free 6 months after nephrectomy. Since high-grade renal MTSCC may have an aggressive clinical course, such patients should be observed carefully after radical nephrectomy.https://www.karger.com/Article/FullText/524897renal mucinous tubular and spindle cell carcinomarenal cell carcinomaradical nephrectomy
spellingShingle Kyotaro Fukuta
Ryoichi Nakanishi
Takahiro Moriyama
Hirofumi Izaki
Takumi Kakimoto
Takeshi Oya
Tomoya Fukawa
Kunihisa Yamaguchi
Yasuyo Yamamoto
Masayuki Takahashi
Yasushi Sutou
Hiro-omi Kanayama
High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
Case Reports in Oncology
renal mucinous tubular and spindle cell carcinoma
renal cell carcinoma
radical nephrectomy
title High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
title_full High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
title_fullStr High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
title_full_unstemmed High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
title_short High-Grade Renal Mucinous Tubular and Spindle Cell Carcinoma
title_sort high grade renal mucinous tubular and spindle cell carcinoma
topic renal mucinous tubular and spindle cell carcinoma
renal cell carcinoma
radical nephrectomy
url https://www.karger.com/Article/FullText/524897
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