Silencing of the rotavirus NSP4 protein decreases the incidence of biliary atresia in murine model.

Silencing of the rotavirus NSP4 protein decreases the incidence of biliary atresia in murine model.

Biliary atresia is a common disease in neonates which causes obstructive jaundice and progressive hepatic fibrosis. Our previous studies indicate that rotavirus infection is an initiator in the pathogenesis of experimental biliary atresia (BA) through the induction of increased nuclear factor-kappaB...

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Bibliographic Details
Main Authors: Jiexiong Feng, Jixin Yang, Shuaiyu Zheng, Yinrong Qiu, Chengwei Chai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158091?pdf=render

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