Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients

Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients

Abstract Background Thrombosis and coagulopathy are highly prevalent in critically ill patients with COVID-19 and increase the risk of death. Immunothrombosis has recently been demonstrated to contribute to the thrombotic events in COVID-19 patients with coagulopathy. As the primary components of im...

Full description

Bibliographic Details
Main Authors: Yue Zhang, Kai Han, Chunjing Du, Rui Li, Jingyuan Liu, Hui Zeng, Liuluan Zhu, Ang Li
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Critical Care
Subjects:
COVID-19
Neutrophil extracellular trap
anaphylatoxin
Carboxypeptidase B
Online Access:https://doi.org/10.1186/s13054-021-03482-z

Similar Items

Similar Items