Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine
Transdermal flunixin meglumine was approved in 2018 to treat pain related to foot-rot in cattle, leading to the question of whether it would be effective as part of a comprehensive pain management strategy for disbudding. To investigate, calves were assigned to three treatment groups: 2% lidocaine c...
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MDPI AG
2022-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/5/533 |
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| author | Tara Gaab Mary Wright Meghann Pierdon |
| author_facet | Tara Gaab Mary Wright Meghann Pierdon |
| author_sort | Tara Gaab |
| collection | DOAJ |
| description | Transdermal flunixin meglumine was approved in 2018 to treat pain related to foot-rot in cattle, leading to the question of whether it would be effective as part of a comprehensive pain management strategy for disbudding. To investigate, calves were assigned to three treatment groups: 2% lidocaine cornual nerve block only (L), lidocaine nerve block +0.45 mg/lb (1 mg/kg) oral meloxicam (M), or lidocaine nerve block +1.5 mg/lb (3.3 mg/kg) transdermal flunixin meglumine (F) (<i>n</i> = 61). Ear flicking (<i>p</i> = 0.001), head shaking (<i>p</i> < 0.001), tail flicking (<i>p</i> < 0.001), interaction with the environment (<i>p</i> < 0.001), grooming (<i>p</i> < 0.01), posture changes (<i>p</i> < 0.05), and standing (<i>p</i> < 0.001) were impacted by the time relative to the procedure. Cortisol levels rose post procedure (<i>p</i> < 0.001). There was no difference in rates of behaviors or cortisol between treatments. These results indicate that calves showed alterations in behavior and cortisol in response to disbudding but not between treatments. We conclude that the pain management protocol for disbudding, which included transdermal flunixin meglumine with a lidocaine cornual nerve block, did not show significant differences from protocols using meloxicam with a lidocaine block, or a lidocaine block alone. |
| first_indexed | 2024-03-09T20:50:11Z |
| format | Article |
| id | doaj.art-0cdd5645d0684d1dbae19743a3b2b33a |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T20:50:11Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-0cdd5645d0684d1dbae19743a3b2b33a2023-11-23T22:36:02ZengMDPI AGAnimals2076-26152022-02-0112553310.3390/ani12050533Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin MeglumineTara Gaab0Mary Wright1Meghann Pierdon2New Bolton Center, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USANew Bolton Center, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USANew Bolton Center, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USATransdermal flunixin meglumine was approved in 2018 to treat pain related to foot-rot in cattle, leading to the question of whether it would be effective as part of a comprehensive pain management strategy for disbudding. To investigate, calves were assigned to three treatment groups: 2% lidocaine cornual nerve block only (L), lidocaine nerve block +0.45 mg/lb (1 mg/kg) oral meloxicam (M), or lidocaine nerve block +1.5 mg/lb (3.3 mg/kg) transdermal flunixin meglumine (F) (<i>n</i> = 61). Ear flicking (<i>p</i> = 0.001), head shaking (<i>p</i> < 0.001), tail flicking (<i>p</i> < 0.001), interaction with the environment (<i>p</i> < 0.001), grooming (<i>p</i> < 0.01), posture changes (<i>p</i> < 0.05), and standing (<i>p</i> < 0.001) were impacted by the time relative to the procedure. Cortisol levels rose post procedure (<i>p</i> < 0.001). There was no difference in rates of behaviors or cortisol between treatments. These results indicate that calves showed alterations in behavior and cortisol in response to disbudding but not between treatments. We conclude that the pain management protocol for disbudding, which included transdermal flunixin meglumine with a lidocaine cornual nerve block, did not show significant differences from protocols using meloxicam with a lidocaine block, or a lidocaine block alone.https://www.mdpi.com/2076-2615/12/5/533transdermal flunixin megluminecalfdisbuddingbehaviorpain |
| spellingShingle | Tara Gaab Mary Wright Meghann Pierdon Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine Animals transdermal flunixin meglumine calf disbudding behavior pain |
| title | Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine |
| title_full | Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine |
| title_fullStr | Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine |
| title_full_unstemmed | Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine |
| title_short | Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine |
| title_sort | behavioral and physiological response to routine thermal disbudding in dairy calves treated with transdermal flunixin meglumine |
| topic | transdermal flunixin meglumine calf disbudding behavior pain |
| url | https://www.mdpi.com/2076-2615/12/5/533 |
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