Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues
Estragole is a volatile terpenoid molecule found in various plants or components, frequently in very high concentrations. It has been demonstrated to increase animal health and output performance effectively. Estragole has been shown to possess antioxidant properties both in vitro and in vivo. These...
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Veterinary Medicine
2023-04-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.vetmedmosul.com/article_177457_e6384571367f5d4c832dff17916ae4c4.pdf |
| _version_ | 1797854644149420032 |
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| author | Mohamad Y. Mahendra Rayudika A. Purba Tri B. Dadi Herinda Pertiwi |
| author_facet | Mohamad Y. Mahendra Rayudika A. Purba Tri B. Dadi Herinda Pertiwi |
| author_sort | Mohamad Y. Mahendra |
| collection | DOAJ |
| description | Estragole is a volatile terpenoid molecule found in various plants or components, frequently in very high concentrations. It has been demonstrated to increase animal health and output performance effectively. Estragole has been shown to possess antioxidant properties both in vitro and in vivo. These properties include the ability to raise GSH and GPx levels, as well as the ability to suppress toxic materials and maintain cellular redox status, MDA activity, and MPO activity. In addition, it produces anti-inflammatory and immunomodulatory effects via the production/release of cytokines, substance P, bradykinin, histamine, serotonin, cytokines, and nitric oxide (NO), and it induces a substantial leukocyte migration. Further, Estragole gives protection against bacteria and viruses. The objective of this review was to briefly discuss the natural sources of Estragole, its chemistry, its extraction, its bioavailability, absorption, distribution, toxicity, and carcinogenicity, and its biomedical effects in vivo or in vitro are discussed in this review. The market for Estragole, as well as its regulatory framework also explained in this study. |
| first_indexed | 2024-04-09T20:10:31Z |
| format | Article |
| id | doaj.art-0cdfef6beb9346f88ffb75cfba9e44f6 |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-04-09T20:10:31Z |
| publishDate | 2023-04-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-0cdfef6beb9346f88ffb75cfba9e44f62023-03-31T23:07:08ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552023-04-0137253754610.33899/ijvs.2022.135092.2445177457Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issuesMohamad Y. Mahendra0Rayudika A. Purba1Tri B. Dadi2Herinda Pertiwi3Department of Health, Faculty of Vocational Studies Airlangga University, Surabaya, IndonesiaSchool of Animal Technology and Innovation, Suranaree University of Technolgy, Nakhon Ratchasima, ThailandDepartment of Veterinary Clinics, Faculty of Veterinary Medicine Airlangga University, Surabaya, IndonesiaDepartment of Health, Faculty of Vocational Studies Airlangga University, Surabaya, IndonesiaEstragole is a volatile terpenoid molecule found in various plants or components, frequently in very high concentrations. It has been demonstrated to increase animal health and output performance effectively. Estragole has been shown to possess antioxidant properties both in vitro and in vivo. These properties include the ability to raise GSH and GPx levels, as well as the ability to suppress toxic materials and maintain cellular redox status, MDA activity, and MPO activity. In addition, it produces anti-inflammatory and immunomodulatory effects via the production/release of cytokines, substance P, bradykinin, histamine, serotonin, cytokines, and nitric oxide (NO), and it induces a substantial leukocyte migration. Further, Estragole gives protection against bacteria and viruses. The objective of this review was to briefly discuss the natural sources of Estragole, its chemistry, its extraction, its bioavailability, absorption, distribution, toxicity, and carcinogenicity, and its biomedical effects in vivo or in vitro are discussed in this review. The market for Estragole, as well as its regulatory framework also explained in this study.https://www.vetmedmosul.com/article_177457_e6384571367f5d4c832dff17916ae4c4.pdfanti-inflammatoryantioxidantestragolehealth-protectiveimmunomodulatory |
| spellingShingle | Mohamad Y. Mahendra Rayudika A. Purba Tri B. Dadi Herinda Pertiwi Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues Iraqi Journal of Veterinary Sciences anti-inflammatory antioxidant estragole health-protective immunomodulatory |
| title | Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues |
| title_full | Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues |
| title_fullStr | Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues |
| title_full_unstemmed | Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues |
| title_short | Estragole: A review of its pharmacology, effect on animal health and performance, toxicology, and market regulatory issues |
| title_sort | estragole a review of its pharmacology effect on animal health and performance toxicology and market regulatory issues |
| topic | anti-inflammatory antioxidant estragole health-protective immunomodulatory |
| url | https://www.vetmedmosul.com/article_177457_e6384571367f5d4c832dff17916ae4c4.pdf |
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