Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood–Brain Barrier

Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood–Brain Barrier

Breast cancer brain metastasis is a major clinical challenge and is associated with a dismal prognosis. Understanding the mechanisms underlying the early stages of brain metastasis can provide opportunities to develop efficient diagnostics and therapeutics for this significant clinical challenge. We...

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Bibliographic Details
Main Authors: Golnaz Morad, Cassandra C. Daisy, Hasan H. Otu, Towia A. Libermann, Simon T. Dillon, Marsha A. Moses
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
brain metastasis
extracellular vesicles
microRNA
blood–brain barrier
Online Access:https://www.mdpi.com/1422-0067/21/11/3851

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