Antifungal activity of water-stable copper-containing metal-organic frameworks

Although metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially in...

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Main Authors: Supaporn Bouson, Atiweena Krittayavathananon, Nutthaphon Phattharasupakun, Patcharaporn Siwayaprahm, Montree Sawangphruk
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170654
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author Supaporn Bouson
Atiweena Krittayavathananon
Nutthaphon Phattharasupakun
Patcharaporn Siwayaprahm
Montree Sawangphruk
author_facet Supaporn Bouson
Atiweena Krittayavathananon
Nutthaphon Phattharasupakun
Patcharaporn Siwayaprahm
Montree Sawangphruk
author_sort Supaporn Bouson
collection DOAJ
description Although metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially interesting, is investigated against Candida albicans, Aspergillus niger, Aspergillus oryzae and Fusarium oxysporum. The Cu-BTC MOF can effectively inhibit the growth rate of C. albicans and remarkably inhibit the spore growth of A. niger, A. oryzae and F. oxysporum. This finding shows the potential of using Cu-BTC MOF as a strong biocidal material against representative yeasts and moulds that are commonly found in the food and agricultural industries.
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spelling doaj.art-0ce2d7117b8c413db5fbc2ce17915dbc2022-12-22T01:25:00ZengThe Royal SocietyRoyal Society Open Science2054-57032017-01-0141010.1098/rsos.170654170654Antifungal activity of water-stable copper-containing metal-organic frameworksSupaporn BousonAtiweena KrittayavathananonNutthaphon PhattharasupakunPatcharaporn SiwayaprahmMontree SawangphrukAlthough metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially interesting, is investigated against Candida albicans, Aspergillus niger, Aspergillus oryzae and Fusarium oxysporum. The Cu-BTC MOF can effectively inhibit the growth rate of C. albicans and remarkably inhibit the spore growth of A. niger, A. oryzae and F. oxysporum. This finding shows the potential of using Cu-BTC MOF as a strong biocidal material against representative yeasts and moulds that are commonly found in the food and agricultural industries.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170654copper-based benzenetricarboxylatemetal-organic frameworksporous coordination polymersantifungalantimicrobial
spellingShingle Supaporn Bouson
Atiweena Krittayavathananon
Nutthaphon Phattharasupakun
Patcharaporn Siwayaprahm
Montree Sawangphruk
Antifungal activity of water-stable copper-containing metal-organic frameworks
Royal Society Open Science
copper-based benzenetricarboxylate
metal-organic frameworks
porous coordination polymers
antifungal
antimicrobial
title Antifungal activity of water-stable copper-containing metal-organic frameworks
title_full Antifungal activity of water-stable copper-containing metal-organic frameworks
title_fullStr Antifungal activity of water-stable copper-containing metal-organic frameworks
title_full_unstemmed Antifungal activity of water-stable copper-containing metal-organic frameworks
title_short Antifungal activity of water-stable copper-containing metal-organic frameworks
title_sort antifungal activity of water stable copper containing metal organic frameworks
topic copper-based benzenetricarboxylate
metal-organic frameworks
porous coordination polymers
antifungal
antimicrobial
url https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.170654
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AT atiweenakrittayavathananon antifungalactivityofwaterstablecoppercontainingmetalorganicframeworks
AT nutthaphonphattharasupakun antifungalactivityofwaterstablecoppercontainingmetalorganicframeworks
AT patcharapornsiwayaprahm antifungalactivityofwaterstablecoppercontainingmetalorganicframeworks
AT montreesawangphruk antifungalactivityofwaterstablecoppercontainingmetalorganicframeworks