Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report
Pancreatic cancer is a malignant neoplasm of the pancreas. It does not cause any symptoms in the early stage, and later symptoms are nonspecific, thus the disease is usually diagnosed when already advanced. In 2008, pancreatic cancer ranked eighth on the list of the 10 most common cancers among men...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2011-08-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/330775 |
| _version_ | 1819126454411067392 |
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| author | Željko Soldić Daniela Žitnjak Ante Bolanča Zvonko Kusić |
| author_facet | Željko Soldić Daniela Žitnjak Ante Bolanča Zvonko Kusić |
| author_sort | Željko Soldić |
| collection | DOAJ |
| description | Pancreatic cancer is a malignant neoplasm of the pancreas. It does not cause any symptoms in the early stage, and later symptoms are nonspecific, thus the disease is usually diagnosed when already advanced. In 2008, pancreatic cancer ranked eighth on the list of the 10 most common cancers among men in Croatia and tenth on the list of the most common cancers among Croatian women. Pancreatic cancer has a poor prognosis, with a survival time of only 6–8 months for metastatic disease. Gemcitabine is the standard chemotherapeutic option. Other chemotherapeutic agents include5-fluorouracil and leucovorin. In this paper, we present a case of a patient diagnosed with locally advanced and metastatic pancreatic cancer, who is still alive and currently receives his fourth line of chemotherapy 5 years after the diagnosis. Following disease progression on gemcitabine chemotherapy, he was treated with chemoradiotherapy which, however, had no effect. We then applied cisplatin monochemotherapy which offered excellent disease control, was well tolerated by the patient and, although somewhat obsolete in this form, showed to be a valuable chemotherapeutic option. |
| first_indexed | 2024-12-22T07:56:17Z |
| format | Article |
| id | doaj.art-0ce40a82dbd04b348c404615df04dc92 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-22T07:56:17Z |
| publishDate | 2011-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-0ce40a82dbd04b348c404615df04dc922022-12-21T18:33:21ZengKarger PublishersCase Reports in Oncology1662-65752011-08-014236737010.1159/000330775330775Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case ReportŽeljko SoldićDaniela ŽitnjakAnte BolančaZvonko KusićPancreatic cancer is a malignant neoplasm of the pancreas. It does not cause any symptoms in the early stage, and later symptoms are nonspecific, thus the disease is usually diagnosed when already advanced. In 2008, pancreatic cancer ranked eighth on the list of the 10 most common cancers among men in Croatia and tenth on the list of the most common cancers among Croatian women. Pancreatic cancer has a poor prognosis, with a survival time of only 6–8 months for metastatic disease. Gemcitabine is the standard chemotherapeutic option. Other chemotherapeutic agents include5-fluorouracil and leucovorin. In this paper, we present a case of a patient diagnosed with locally advanced and metastatic pancreatic cancer, who is still alive and currently receives his fourth line of chemotherapy 5 years after the diagnosis. Following disease progression on gemcitabine chemotherapy, he was treated with chemoradiotherapy which, however, had no effect. We then applied cisplatin monochemotherapy which offered excellent disease control, was well tolerated by the patient and, although somewhat obsolete in this form, showed to be a valuable chemotherapeutic option.http://www.karger.com/Article/FullText/330775CisplatinCancerPancreasLiver metastases |
| spellingShingle | Željko Soldić Daniela Žitnjak Ante Bolanča Zvonko Kusić Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report Case Reports in Oncology Cisplatin Cancer Pancreas Liver metastases |
| title | Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report |
| title_full | Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report |
| title_fullStr | Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report |
| title_full_unstemmed | Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report |
| title_short | Long-Time Survival of a Patient with Metastatic Pancreatic Cancer: A Case Report |
| title_sort | long time survival of a patient with metastatic pancreatic cancer a case report |
| topic | Cisplatin Cancer Pancreas Liver metastases |
| url | http://www.karger.com/Article/FullText/330775 |
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