Expression Profiling of Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma Patients: Biomarkers Predicting Overall Survival

Expression Profiling of Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma Patients: Biomarkers Predicting Overall Survival

The interest in liquid biopsy is growing because it could represent a non-invasive prognostic or predictive tool for clinical outcome in patients with pancreatic ductal adenocarcinoma (PDAC), an aggressive and lethal disease. In this pilot study, circulating tumor cells (CTCs), CD16 positive atypica...

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Bibliographic Details
Main Authors: Consuelo Amantini, Maria Beatrice Morelli, Massimo Nabissi, Francesco Piva, Oliviero Marinelli, Federica Maggi, Francesca Bianchi, Alessandro Bittoni, Rossana Berardi, Riccardo Giampieri, Giorgio Santoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
circulating tumor cells
pancreatic cancer
overall survival
gene signature
digital droplet PCR
atypical CTC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00874/full

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