Computational Approach to Elucidating Insulin–Protamine Binding Interactions and Dynamics in Insulin NPH Formulations

Computational Approach to Elucidating Insulin–Protamine Binding Interactions and Dynamics in Insulin NPH Formulations

Bibliographic Details
Main Authors:	Ketan Kumar Rohilla, Manoj Kumar Pandey
Format:	Article
Language:	English
Published:	American Chemical Society 2024-01-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.3c08445

Similar Items

Insulin glargine compared to neutral protamine Hagedorn (NPH) insulin in patients with type-2 diabetes uncontrolled with oral anti-diabetic agents alone in Hong Kong: a cost-effectiveness analysis
by: E. Lau, et al.
Published: (2019-07-01)

Assessment of Efficacy of NPH Insulin in Cartridges Injection Technique
by: N.N. Zherdeva
Published: (2012-02-01)

Comparison between basal insulin glargine and NPH insulin in patients with diabetes type 1 on conventional intensive insulin therapy
by: Pešić Milica, et al.
Published: (2007-01-01)

Improved glycaemic control by switching from insulin NPH to insulin glargine: a retrospective observational study
by: Tetlow Anthony P, et al.
Published: (2009-01-01)

Health economic evaluations comparing insulin glargine with NPH insulin in patients with type 1 diabetes: a systematic review
by: Dippel Franz-Werner, et al.
Published: (2011-10-01)

Successful desensitization with human insulin in a patient with an insulin allergy and hypersensitivity to protamine: a case report
by: Pföhler Claudia, et al.
Published: (2008-08-01)

Molecular Dynamics Simulations of Insulin: Elucidating the Conformational Changes that Enable Its Binding.
by: Anastasios Papaioannou, et al.
Published: (2015-01-01)

All-Cause and Cause-Specific Mortality among Users of Basal Insulins NPH, Detemir, and Glargine.
by: Arto Y Strandberg, et al.
Published: (2016-01-01)

Prevention of Postprandial Hyperglycemia by Ophthalmic Nanoparticles Based on Protamine Zinc Insulin in the Rabbit
by: Saori Deguchi, et al.
Published: (2021-03-01)

Effects of combined treatment with rosiglitazone and NPH insulin on carbohydrate metabolism in patients with type 2 diabetes mellitus
by: O A Kandalintseva, et al.
Published: (2008-12-01)

Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin
by: Mahboobeh Yeganeh-Hajahmadi, et al.
Published: (2023-10-01)

Subcutaneous NPH Insulin for Severe Hypertriglyceridemia in a Pregnant Patient with Type V Hyperlipoproteinemia: a Case Report
by: Mustafa Kemal Balcı, et al.
Published: (2012-06-01)

Secretagogin Regulates Insulin Signaling by Direct Insulin Binding
by: Anand Kumar Sharma, et al.
Published: (2019-11-01)

Clinical experience of switching from glargine or neutral protamine Hagedorn insulin to insulin detemir in type 2 diabetes: Observations from the Indian cohort in the A 1 chieve study
by: Subhash Kumar Wangnoo, et al.
Published: (2014-01-01)

Efficacy and safety of insulin lispro protamine suspension as basal supplementation in patients with type 2 diabetes
by: Dario Giugliano, et al.
Published: (2012-06-01)

Estradiol Binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro
by: Robert eRoot-Bernstein, et al.
Published: (2014-07-01)

A new long-acting insulin (HOE901) demonstrates less nocturnal hypoglycaemia when compared with protamine insulin in a clinical trial.
by: Matthews, DR, et al.
Published: (1998)

Efficacy of Glargine Insulin Compared with Neutral Protamine Hagedorn Insulin in Patients with Type 2 Diabetes not Controlled with Oral Hypoglycemics: A Cohort Study
by: Ebtihal Bilal, et al.
Published: (2023-08-01)

Association of initiation of basal insulin analogues V/S NPH insulin with hypoglycemia related emergency department visits or hospital admissions and with glycemic control in patients with type 2 DM
by: Kasia J Lipska, et al.
Published: (2019-01-01)

Long‐term field study of lispro and neutral protamine Hagedorn insulins treatment in dogs with diabetes mellitus
by: Sharon Kuzi, et al.
Published: (2023-03-01)

Electronic medical record cancer incidence over six years comparing new users of glargine with new users of NPH insulin.
by: Soo Lim, et al.
Published: (2014-01-01)

Study rationale and design of the EANITIATE study (EmpAgliflozin compared to NPH Insulin for sTeroId diAbeTEs) - a randomized, controlled, multicenter trial of safety and efficacy of treatment with empagliflozin compared with NPH-insulin in patients with newly onset diabetes following initiation of glucocorticoid treatment
by: Carina Kirstine Klarskov, et al.
Published: (2020-06-01)

Elucidating the Activation Mechanism of the Insulin-Family Proteins with Molecular Dynamics Simulations.
by: Anastasios Papaioannou, et al.
Published: (2016-01-01)

The effect of cold atmospheric plasma (NO) alone and in combination with NPH insulin on the full-thickness excisional wound healing in a diabetic rat model
by: A Curukoglu, et al.
Published: (2023-04-01)

iNPH—the mystery resolving
by: Ville Leinonen, et al.
Published: (2021-03-01)

Does NPH equal ischemia?
by: Messier Arthur, et al.
Published: (2007-12-01)

Insulin degludec/insulin aspart is the first co-formulation of basal and prandial insulin analogues
by: Ivan Ivanovich Dedov, et al.
Published: (2014-12-01)

Evaluating the cost-effectiveness of insulin detemir versus neutral protamine Hagedorn insulin in patients with type 1 or type 2 diabetes in the UK using a short-term modeling approach
by: Pollock RF, et al.
Published: (2018-05-01)

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
by: Zhening Zhang, et al.
Published: (2018-03-01)

Protamine 1 to protamine 2 ratio correlates with dynamic aspects of DNA fragmentation in human sperm.
by: García-Peiró, A, et al.
Published: (2011)

Probable NPH in patients with clinical AD: further support for the AD-NPH syndrome and CSF circulatory failure
by: Saul T, et al.
Published: (2004-12-01)

Pragmatic use of insulin degludec/insulin aspart co-formulation: A multinational consensus statement
by: Sanjay Kalra, et al.
Published: (2016-01-01)

Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations
by: Yui Ohno, et al.
Published: (2019-10-01)

Indirect comparison of lixisenatide versus neutral protamine Hagedorn insulin as add-on to metformin and sulphonylurea in patients with type 2 diabetes mellitus
by: Fournier, Marie, et al.
Published: (2014-10-01)

Modeling of Insulin Receptor Modeling of Insulin Receptor Binding & Recycling Binding & Recycling Subsystem
by: Ismail, Nor Faekah
Published: (2007)

Identification of Host Insulin Binding Sites on Schistosoma japonicum Insulin Receptors.
by: Rachel J Stephenson, et al.
Published: (2016-01-01)

Update on the Cognitive Presentations of iNPH for Clinicians
by: Tobias Langheinrich, et al.
Published: (2022-07-01)

The Clinical Utility of the MOCA in iNPH Assessment
by: Eric Wesner, et al.
Published: (2022-05-01)

Pre- and postoperative diffusion tensor imaging in NPH
by: Hoffmann Karl-Titus, et al.
Published: (2009-02-01)

Insulin-Like Growth Factor Binding Protein-3 Binds to Histone 3
by: Apurva Bhardwaj, et al.
Published: (2021-01-01)