Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis
The<i> in vivo</i> evaluation of trabecular bone structure could be useful in the diagnosis of osteoporosis for the characterization of therapeutic response and understanding the role of parameters other than bone mineral density (BMD) in defining skeletal status. This study was made t...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2007-01-01
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| Series: | Journal of Medical Physics |
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| Online Access: | http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=4;spage=161;epage=168;aulast=Karunanithi |
| _version_ | 1818128413450305536 |
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| author | Karunanithi R Ganesan S Panicker T.M.R Korath M Jagadeesan K |
| author_facet | Karunanithi R Ganesan S Panicker T.M.R Korath M Jagadeesan K |
| author_sort | Karunanithi R |
| collection | DOAJ |
| description | The<i> in vivo</i> evaluation of trabecular bone structure could be useful in the diagnosis of osteoporosis for the characterization of therapeutic response and understanding the role of parameters other than bone mineral density (BMD) in defining skeletal status. This study was made to evaluate changes taking place in the trabecular architecture of bone with age and menopausal status in women. The findings are compared with the femoral neck bone as well as the trochantar bone mineral density determined by dual energy X-ray absorptiometry (DXA), which is a standard reference test for evaluation of osteoporosis. Seventy females were recruited for the study, 25 pre-menopausal (mean age ± SD: 39.4 ± 3.8) and 45 postmenopausal (mean age ± SD: 57.9 ± 7.9) women. The right femoral neck bone mineral density was measured for them by dual energy X-ray absorptiometry (DXA). For the same individuals, lateral view radiographs of the right calcaneum were taken as well. The radiographs were digitized and the region of interest (ROI) of 256 x 256 pixels was selected, the run-length matrix was computed for calculating seven parameters [Table 1] and the two-dimensional fast Fourier transform of the image was calculated. Using the FFT, the power spectral density (PSD) was derived and the root mean square (RMS) value was determined. Our results confirm that age has a significant influence on the texture of the trabecular bone and bone mineral density. |
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| format | Article |
| id | doaj.art-0ce8b00c67a44167b1582a91e4b594ea |
| institution | Directory Open Access Journal |
| issn | 0971-6203 |
| language | English |
| last_indexed | 2024-12-11T07:32:51Z |
| publishDate | 2007-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Physics |
| spelling | doaj.art-0ce8b00c67a44167b1582a91e4b594ea2022-12-22T01:15:46ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62032007-01-01324161168Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosisKarunanithi RGanesan SPanicker T.M.RKorath MJagadeesan KThe<i> in vivo</i> evaluation of trabecular bone structure could be useful in the diagnosis of osteoporosis for the characterization of therapeutic response and understanding the role of parameters other than bone mineral density (BMD) in defining skeletal status. This study was made to evaluate changes taking place in the trabecular architecture of bone with age and menopausal status in women. The findings are compared with the femoral neck bone as well as the trochantar bone mineral density determined by dual energy X-ray absorptiometry (DXA), which is a standard reference test for evaluation of osteoporosis. Seventy females were recruited for the study, 25 pre-menopausal (mean age ± SD: 39.4 ± 3.8) and 45 postmenopausal (mean age ± SD: 57.9 ± 7.9) women. The right femoral neck bone mineral density was measured for them by dual energy X-ray absorptiometry (DXA). For the same individuals, lateral view radiographs of the right calcaneum were taken as well. The radiographs were digitized and the region of interest (ROI) of 256 x 256 pixels was selected, the run-length matrix was computed for calculating seven parameters [Table 1] and the two-dimensional fast Fourier transform of the image was calculated. Using the FFT, the power spectral density (PSD) was derived and the root mean square (RMS) value was determined. Our results confirm that age has a significant influence on the texture of the trabecular bone and bone mineral density.http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=4;spage=161;epage=168;aulast=KarunanithiBone mineral densityosteoporosistexture analysistrabecular architecture |
| spellingShingle | Karunanithi R Ganesan S Panicker T.M.R Korath M Jagadeesan K Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis Journal of Medical Physics Bone mineral density osteoporosis texture analysis trabecular architecture |
| title | Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis |
| title_full | Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis |
| title_fullStr | Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis |
| title_full_unstemmed | Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis |
| title_short | Assessment of bone mineral density by DXA and the trabecular microarchitecture of the calcaneum by texture analysis in pre- and postmenopausal women in the evaluation of osteoporosis |
| title_sort | assessment of bone mineral density by dxa and the trabecular microarchitecture of the calcaneum by texture analysis in pre and postmenopausal women in the evaluation of osteoporosis |
| topic | Bone mineral density osteoporosis texture analysis trabecular architecture |
| url | http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=4;spage=161;epage=168;aulast=Karunanithi |
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