The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis
Objective The aim of the meta-analysis was to explore effects of resistance exercise (RE) on body composition and physical function in patients with prostate cancer (PCa).Data sources We searched the electronic databases of Pubmed, Embase, Cochrane, and web of science. Published studies have been co...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | The Aging Male |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/13685538.2022.2146670 |
| _version_ | 1828098874295713792 |
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| author | Siyu Tian Meng Ding Hongfu Sun |
| author_facet | Siyu Tian Meng Ding Hongfu Sun |
| author_sort | Siyu Tian |
| collection | DOAJ |
| description | Objective The aim of the meta-analysis was to explore effects of resistance exercise (RE) on body composition and physical function in patients with prostate cancer (PCa).Data sources We searched the electronic databases of Pubmed, Embase, Cochrane, and web of science. Published studies have been collected from these databases. Search terms include resistance training, strength training, RE, androgen suppression therapy, androgen deprivation therapy and PCa, with a deadline of 31 March 2022.Main results These studies showed significant improvements of body composition(Lean body mass MD: 1.12 95% CI [0.48, 1.76], p < 0.01; Body fat rate MD: –1.12 95% CI [–1.99,–0.24], p < 0.05; Appendicular skeletal mass MD: 0.74 95% CI [0.45, 1.03], p < 0.01) and physical function (leg press MD: 77.95 95% CI [38.90, 117.00], p < 0.01; stair climb MD:–0.30 95% CI [–0.49, –0.12], p < 0.01). In addition, the improvement of Body fat mass (MD: –0.21 95% CI [–0.79, 0.37], p > 0.05), 400 m walk (MD: –21.74 95% CI [–45.53, 2.05], p > 0.05) and times up and go (MD: –0.50 95% CI [–1.03, 0.03], p > 0.05) were not obvious. Subgroup analyses showed that RE for ≥ 6 months (compared with RE intervention for < 6 months) and starting exercise immediately after androgen deprivation therapy (ADT) (compared with delayed exercise after ADT) resulted in more significant improvements in body composition. Furthermore, the results showed that the exercise intensity of 8–12 RM significantly improved body composition.Conclusions RE seems to be a promising approach in order to improve body composition and physical function in PCa patients to offset their treatment-related side effects. RE should be used as a means of rehabilitation and care for PCa. Starting exercise immediately after ADT and extending exercise time while choosing the right intensity can better improve the patients’ body composition and function. Registration number INPLASY202280019 |
| first_indexed | 2024-04-11T08:08:50Z |
| format | Article |
| id | doaj.art-0ce92fae043b41a2aa65d36870b04a0c |
| institution | Directory Open Access Journal |
| issn | 1368-5538 1473-0790 |
| language | English |
| last_indexed | 2024-04-11T08:08:50Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | The Aging Male |
| spelling | doaj.art-0ce92fae043b41a2aa65d36870b04a0c2022-12-22T04:35:26ZengTaylor & Francis GroupThe Aging Male1368-55381473-07902022-12-0125128129210.1080/13685538.2022.2146670The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysisSiyu Tian0Meng Ding1Hongfu Sun2College of Physical Education, Shandong Normal University, Jinan, ChinaCollege of Physical Education, Shandong Normal University, Jinan, ChinaInstitute of Great Health Products Research, Shandong Academy of Chinese Medicine, Jinan, ChinaObjective The aim of the meta-analysis was to explore effects of resistance exercise (RE) on body composition and physical function in patients with prostate cancer (PCa).Data sources We searched the electronic databases of Pubmed, Embase, Cochrane, and web of science. Published studies have been collected from these databases. Search terms include resistance training, strength training, RE, androgen suppression therapy, androgen deprivation therapy and PCa, with a deadline of 31 March 2022.Main results These studies showed significant improvements of body composition(Lean body mass MD: 1.12 95% CI [0.48, 1.76], p < 0.01; Body fat rate MD: –1.12 95% CI [–1.99,–0.24], p < 0.05; Appendicular skeletal mass MD: 0.74 95% CI [0.45, 1.03], p < 0.01) and physical function (leg press MD: 77.95 95% CI [38.90, 117.00], p < 0.01; stair climb MD:–0.30 95% CI [–0.49, –0.12], p < 0.01). In addition, the improvement of Body fat mass (MD: –0.21 95% CI [–0.79, 0.37], p > 0.05), 400 m walk (MD: –21.74 95% CI [–45.53, 2.05], p > 0.05) and times up and go (MD: –0.50 95% CI [–1.03, 0.03], p > 0.05) were not obvious. Subgroup analyses showed that RE for ≥ 6 months (compared with RE intervention for < 6 months) and starting exercise immediately after androgen deprivation therapy (ADT) (compared with delayed exercise after ADT) resulted in more significant improvements in body composition. Furthermore, the results showed that the exercise intensity of 8–12 RM significantly improved body composition.Conclusions RE seems to be a promising approach in order to improve body composition and physical function in PCa patients to offset their treatment-related side effects. RE should be used as a means of rehabilitation and care for PCa. Starting exercise immediately after ADT and extending exercise time while choosing the right intensity can better improve the patients’ body composition and function. Registration number INPLASY202280019https://www.tandfonline.com/doi/10.1080/13685538.2022.2146670Prostate cancerADTREbody compositionphysical function |
| spellingShingle | Siyu Tian Meng Ding Hongfu Sun The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis The Aging Male Prostate cancer ADT RE body composition physical function |
| title | The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis |
| title_full | The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis |
| title_fullStr | The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis |
| title_full_unstemmed | The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis |
| title_short | The effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy: an update systematic review and meta-analysis |
| title_sort | effects of resistance exercise on body composition and physical function in prostate cancer patients undergoing androgen deprivation therapy an update systematic review and meta analysis |
| topic | Prostate cancer ADT RE body composition physical function |
| url | https://www.tandfonline.com/doi/10.1080/13685538.2022.2146670 |
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