A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy
CONTEXT: The omentoenteropexy technique was developed as an alternative method for intestinal neovascularization, due to the angiogenic properties of factors from the omentum. OBJECTIVES: This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)
2011-12-01
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| Series: | Arquivos de Gastroenterologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000400012&lng=en&tlng=en |
| _version_ | 1819175492249452544 |
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| author | Pedro Muñoz Fernandez Fabíola Pollachi Rafael Alves Cordeiro Ana Maria A. A Mader Wilson Roberto Catapani |
| author_facet | Pedro Muñoz Fernandez Fabíola Pollachi Rafael Alves Cordeiro Ana Maria A. A Mader Wilson Roberto Catapani |
| author_sort | Pedro Muñoz Fernandez |
| collection | DOAJ |
| description | CONTEXT: The omentoenteropexy technique was developed as an alternative method for intestinal neovascularization, due to the angiogenic properties of factors from the omentum. OBJECTIVES: This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromiotomy with and without omentoenteropexy. METHOD: Thirty rats were operated on, after being divided into three groups, namely GI, GII and GIII with 10 rats each. In the GI rats were submitted to omentoenteropexy; rats in GII were submitted only to a seromiotomy, and in the GIII only laparotomy. Sixty days after the first surgery, the animals were sacrificed and a segment of intestine was removed for histology using Masson's trichrome technique and morphometric study of intestinal mucosa. RESULTS: The histological findings showed that seromiotomy with or without omentoenteropexy increased the length of intestinal villi when compared with GIII (only laparotomy) (analysis of variance: P = 0.0068; GI 38.88 ± 4.17; GII 39.41± 6.33; GIII 31.85 ± 5.56; GI = GII P>0.05; GII>GIII P<0.05; GI>GIII P<0.001). CONCLUSION: No differences were demonstrated in relation to crypt depths between the groups (P = 0.60). Ongoing studies are being set forth by our group to add more data on the role of omentopexy as a tool to promote neovascularization and intestinal mucosal growth. |
| first_indexed | 2024-12-22T20:55:43Z |
| format | Article |
| id | doaj.art-0cea31d11673410cb41e81adff86380f |
| institution | Directory Open Access Journal |
| issn | 1678-4219 |
| language | English |
| last_indexed | 2024-12-22T20:55:43Z |
| publishDate | 2011-12-01 |
| publisher | Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) |
| record_format | Article |
| series | Arquivos de Gastroenterologia |
| spelling | doaj.art-0cea31d11673410cb41e81adff86380f2022-12-21T18:12:57ZengInstituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)Arquivos de Gastroenterologia1678-42192011-12-0148428328510.1590/S0004-28032011000400012S0004-28032011000400012A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexyPedro Muñoz Fernandez0Fabíola Pollachi1Rafael Alves Cordeiro2Ana Maria A. A Mader3Wilson Roberto Catapani4Faculdade de Medicina do ABCFaculdade de Medicina do ABCFaculdade de Medicina do ABCFaculdade de Medicina do ABCFaculdade de Medicina do ABCCONTEXT: The omentoenteropexy technique was developed as an alternative method for intestinal neovascularization, due to the angiogenic properties of factors from the omentum. OBJECTIVES: This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromiotomy with and without omentoenteropexy. METHOD: Thirty rats were operated on, after being divided into three groups, namely GI, GII and GIII with 10 rats each. In the GI rats were submitted to omentoenteropexy; rats in GII were submitted only to a seromiotomy, and in the GIII only laparotomy. Sixty days after the first surgery, the animals were sacrificed and a segment of intestine was removed for histology using Masson's trichrome technique and morphometric study of intestinal mucosa. RESULTS: The histological findings showed that seromiotomy with or without omentoenteropexy increased the length of intestinal villi when compared with GIII (only laparotomy) (analysis of variance: P = 0.0068; GI 38.88 ± 4.17; GII 39.41± 6.33; GIII 31.85 ± 5.56; GI = GII P>0.05; GII>GIII P<0.05; GI>GIII P<0.001). CONCLUSION: No differences were demonstrated in relation to crypt depths between the groups (P = 0.60). Ongoing studies are being set forth by our group to add more data on the role of omentopexy as a tool to promote neovascularization and intestinal mucosal growth.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000400012&lng=en&tlng=enOmentocirurgiaMucosa intestinalRatos |
| spellingShingle | Pedro Muñoz Fernandez Fabíola Pollachi Rafael Alves Cordeiro Ana Maria A. A Mader Wilson Roberto Catapani A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy Arquivos de Gastroenterologia Omento cirurgia Mucosa intestinal Ratos |
| title | A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| title_full | A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| title_fullStr | A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| title_full_unstemmed | A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| title_short | A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| title_sort | morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy |
| topic | Omento cirurgia Mucosa intestinal Ratos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000400012&lng=en&tlng=en |
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