Primary intracerebral melanoma: A case report
Primary intracranial malignant melanoma is an extremely rare entity These aggressive tumors are derived from the melanocytes of leptomeninges or their precursor cells and can give metastasis to other organs. It effects mostly middle aged males and represents a very poor prognosis with median surviva...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor
2021-01-01
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| Series: | Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2021/1821-19252183053P.pdf |
| _version_ | 1811335474610962432 |
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| author | Paunović Aleksandra Lazić Igor Milisavljević Filip Miljković Aleksandar Nedeljković Žarko Bogdanović Ivan Rakonjac Marija Ilić Rosanda |
| author_facet | Paunović Aleksandra Lazić Igor Milisavljević Filip Miljković Aleksandar Nedeljković Žarko Bogdanović Ivan Rakonjac Marija Ilić Rosanda |
| author_sort | Paunović Aleksandra |
| collection | DOAJ |
| description | Primary intracranial malignant melanoma is an extremely rare entity These aggressive tumors are derived from the melanocytes of leptomeninges or their precursor cells and can give metastasis to other organs. It effects mostly middle aged males and represents a very poor prognosis with median survival less than 1 year. For proper diagnosis, melanoma of other localization must be excluded. Giving the rarity of this tumor, treatment of choice in unclear. We report a case of 43 year old patient with primary intracranial melanoma treated by supramarginal resection followed by whole brain RT, with disease free period of three years following treatment. We strongly advocate for aggressive treatment approach, supramarginal resection whenever safe, adjuvant therapy and frequent check-ups. We also hope to inspire future studies on larger sample to in order to establish an adequate therapy protocols. |
| first_indexed | 2024-04-13T17:24:43Z |
| format | Article |
| id | doaj.art-0ceac77faec94098aeea40790a3c9d3d |
| institution | Directory Open Access Journal |
| issn | 1821-1925 2406-131X |
| language | English |
| last_indexed | 2024-04-13T17:24:43Z |
| publishDate | 2021-01-01 |
| publisher | Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor |
| record_format | Article |
| series | Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| spelling | doaj.art-0ceac77faec94098aeea40790a3c9d3d2022-12-22T02:37:49ZengSpecijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma ZlatiborMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"1821-19252406-131X2021-01-012683537010.5937/mgiszm2183053P1821-19252183053PPrimary intracerebral melanoma: A case reportPaunović Aleksandra0Lazić Igor1Milisavljević Filip2Miljković Aleksandar3Nedeljković Žarko4Bogdanović Ivan5Rakonjac Marija6Ilić Rosanda7Univerzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Centar za anesteziologiju, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Centar za anesteziologiju, Beograd, SerbiaUniverzitetski Klinički centar Srbije, Neurohirurška klinika, Beograd, SerbiaPrimary intracranial malignant melanoma is an extremely rare entity These aggressive tumors are derived from the melanocytes of leptomeninges or their precursor cells and can give metastasis to other organs. It effects mostly middle aged males and represents a very poor prognosis with median survival less than 1 year. For proper diagnosis, melanoma of other localization must be excluded. Giving the rarity of this tumor, treatment of choice in unclear. We report a case of 43 year old patient with primary intracranial melanoma treated by supramarginal resection followed by whole brain RT, with disease free period of three years following treatment. We strongly advocate for aggressive treatment approach, supramarginal resection whenever safe, adjuvant therapy and frequent check-ups. We also hope to inspire future studies on larger sample to in order to establish an adequate therapy protocols.https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2021/1821-19252183053P.pdf |
| spellingShingle | Paunović Aleksandra Lazić Igor Milisavljević Filip Miljković Aleksandar Nedeljković Žarko Bogdanović Ivan Rakonjac Marija Ilić Rosanda Primary intracerebral melanoma: A case report Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor" |
| title | Primary intracerebral melanoma: A case report |
| title_full | Primary intracerebral melanoma: A case report |
| title_fullStr | Primary intracerebral melanoma: A case report |
| title_full_unstemmed | Primary intracerebral melanoma: A case report |
| title_short | Primary intracerebral melanoma: A case report |
| title_sort | primary intracerebral melanoma a case report |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2021/1821-19252183053P.pdf |
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