Prevalence of Cancer Predisposition Germline Variants in Male Breast Cancer Patients: Results of the German Consortium for Hereditary Breast and Ovarian Cancer

Prevalence of Cancer Predisposition Germline Variants in Male Breast Cancer Patients: Results of the German Consortium for Hereditary Breast and Ovarian Cancer

Male breast cancer (mBC) is associated with a high prevalence of pathogenic variants (PVs) in the <i>BRCA2</i> gene; however, data regarding other BC predisposition genes are limited. In this retrospective multicenter study, we investigated the prevalence of PVs in <i>BRCA1/2</i...

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Bibliographic Details
Main Authors: Muriel Rolfes, Julika Borde, Kathrin Möllenhoff, Mohamad Kayali, Corinna Ernst, Andrea Gehrig, Christian Sutter, Juliane Ramser, Dieter Niederacher, Judit Horváth, Norbert Arnold, Alfons Meindl, Bernd Auber, Andreas Rump, Shan Wang-Gohrke, Julia Ritter, Julia Hentschel, Holger Thiele, Janine Altmüller, Peter Nürnberg, Kerstin Rhiem, Christoph Engel, Barbara Wappenschmidt, Rita K. Schmutzler, Eric Hahnen, Jan Hauke
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
breast neoplasms
male breast cancer
breast cancer predisposition genes
genetic testing
familial breast cancer
Online Access:https://www.mdpi.com/2072-6694/14/13/3292

Internet

https://www.mdpi.com/2072-6694/14/13/3292

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