Mitochondrial Respiratory Chain Dysfunction—A Hallmark Pathology of Idiopathic Parkinson’s Disease?

Parkinson’s disease (PD) is the most common age-dependent neurodegenerative synucleinopathy. Loss of dopaminergic neurons of the substantia nigra pars compacta, together with region- and cell-specific aggregations of α-synuclein are considered main pathological hallmarks of PD, but its etiopathogene...

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Main Authors: Irene H. Flønes, Charalampos Tzoulis
格式: 文件
语言:English
出版: Frontiers Media S.A. 2022-04-01
丛编:Frontiers in Cell and Developmental Biology
主题:
在线阅读:https://www.frontiersin.org/articles/10.3389/fcell.2022.874596/full