Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalati...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/13/6/1102 |
| _version_ | 1797609754875396096 |
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| author | Seungjin Yu Goeun Choi Jin-Ho Choy |
| author_facet | Seungjin Yu Goeun Choi Jin-Ho Choy |
| author_sort | Seungjin Yu |
| collection | DOAJ |
| description | Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging. |
| first_indexed | 2024-03-11T06:04:48Z |
| format | Article |
| id | doaj.art-0cec4122ed5e47fc9446c4bb45888e6e |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-11T06:04:48Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-0cec4122ed5e47fc9446c4bb45888e6e2023-11-17T13:01:34ZengMDPI AGNanomaterials2079-49912023-03-01136110210.3390/nano13061102Multifunctional Layered Double Hydroxides for Drug Delivery and ImagingSeungjin Yu0Goeun Choi1Jin-Ho Choy2Department of Nanobiomedical Science and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Republic of KoreaDepartment of Nanobiomedical Science and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 31116, Republic of KoreaIntelligent Nanohybrid Materials Laboratory (INML), Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Republic of KoreaTwo-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging.https://www.mdpi.com/2079-4991/13/6/1102layered double hydroxideinorganic nano vehicledrug deliverybio-imagingtherapydiagnosis |
| spellingShingle | Seungjin Yu Goeun Choi Jin-Ho Choy Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging Nanomaterials layered double hydroxide inorganic nano vehicle drug delivery bio-imaging therapy diagnosis |
| title | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
| title_full | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
| title_fullStr | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
| title_full_unstemmed | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
| title_short | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
| title_sort | multifunctional layered double hydroxides for drug delivery and imaging |
| topic | layered double hydroxide inorganic nano vehicle drug delivery bio-imaging therapy diagnosis |
| url | https://www.mdpi.com/2079-4991/13/6/1102 |
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