High-Throughput Transcriptomics of <i>Celf1</i> Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology

High-Throughput Transcriptomics of <i>Celf1</i> Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology

Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to characterize the genes linked to this developmental defect and to define their downstream pathways that are relevant to lens biology and path...

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Bibliographic Details
Main Authors: Archana D. Siddam, Matthieu Duot, Sarah Y. Coomson, Deepti Anand, Sandeep Aryal, Bailey A. T. Weatherbee, Yann Audic, Luc Paillard, Salil A. Lachke
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
lens
eye
cataracts
RNA-binding protein
Cugbp1
development
Online Access:https://www.mdpi.com/2073-4409/12/7/1070

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