Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function

Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function

Abstract Background Non-coding gene regulatory enhancers are essential to transcription in mammalian cells. As a result, a large variety of experimental and computational strategies have been developed to identify cis-regulatory enhancer sequences. Given the differences in the biological signals ass...

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Bibliographic Details
Main Authors: Mary Lauren Benton, Sai Charan Talipineni, Dennis Kostka, John A. Capra
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Genomics
Subjects:
Enhancer identification
Gene regulation
Cis-regulatory elements
Online Access:http://link.springer.com/article/10.1186/s12864-019-5779-x

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