METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

N6-metyladenosine (m6A) RNA methylation has been proven to be involved in diverse biological processes, but its potential roles in the development of lipopolysaccharide (LPS) induced retinal pigment epithelium (RPE) inflammation have not been revealed. In this study, we explored the effects and unde...

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Bibliographic Details
Main Authors: Jiayu Meng, Xianyang Liu, Shiyun Tang, Yusen Liu, Chenyang Zhao, Qian Zhou, Na Li, Shengping Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
METTL3
RPE
inflammation
M6A
NR2F1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.905211/full

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