Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia
Mounting evidence has revealed that abnormal expression of circular RNAs play pivotal roles in many human diseases including preeclampsia (PE). While human sapiens circular RNA 0007121 (hsa_circ_0007121) has been verified to be downregulated in human placental tissues, the underlying mechanisms were...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2020-10-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2020-0230 |
| _version_ | 1819130401077067776 |
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| author | Gai Shukun Sun Li Wang Huiying Yang Ping |
| author_facet | Gai Shukun Sun Li Wang Huiying Yang Ping |
| author_sort | Gai Shukun |
| collection | DOAJ |
| description | Mounting evidence has revealed that abnormal expression of circular RNAs play pivotal roles in many human diseases including preeclampsia (PE). While human sapiens circular RNA 0007121 (hsa_circ_0007121) has been verified to be downregulated in human placental tissues, the underlying mechanisms were still unclear. This research aims to investigate the effect and underlying mechanisms of hsa_circ_0007121 in preeclampsia. |
| first_indexed | 2024-12-22T08:59:01Z |
| format | Article |
| id | doaj.art-0d09666ce1554d41a87a8b77aa9526ab |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-12-22T08:59:01Z |
| publishDate | 2020-10-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-0d09666ce1554d41a87a8b77aa9526ab2022-12-21T18:31:46ZengDe GruyterOpen Medicine2391-54632020-10-011511061107110.1515/med-2020-0230med-2020-0230Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsiaGai Shukun0Sun Li1Wang Huiying2Yang Ping3Department of Obstetrics, Yantai Yuhuangding Hospital, 20 Yudong Road, Zhifu District, Shandong Province, 264000, Yantai, Shandong, ChinaDepartment of Obstetrics, Yantai Yuhuangding Hospital, 20 Yudong Road, Zhifu District, Shandong Province, 264000, Yantai, Shandong, ChinaDepartment of Obstetrics, Yantai Yuhuangding Hospital, 20 Yudong Road, Zhifu District, Shandong Province, 264000, Yantai, Shandong, ChinaDepartment of Obstetrics, Yantai Yuhuangding Hospital, 20 Yudong Road, Zhifu District, Shandong Province, 264000, Yantai, Shandong, ChinaMounting evidence has revealed that abnormal expression of circular RNAs play pivotal roles in many human diseases including preeclampsia (PE). While human sapiens circular RNA 0007121 (hsa_circ_0007121) has been verified to be downregulated in human placental tissues, the underlying mechanisms were still unclear. This research aims to investigate the effect and underlying mechanisms of hsa_circ_0007121 in preeclampsia.https://doi.org/10.1515/med-2020-0230pehsa_circ_0007121mir-182-5p, pgf |
| spellingShingle | Gai Shukun Sun Li Wang Huiying Yang Ping Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia Open Medicine pe hsa_circ_0007121 mir-182-5p, pgf |
| title | Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia |
| title_full | Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia |
| title_fullStr | Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia |
| title_full_unstemmed | Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia |
| title_short | Circular RNA hsa_circ_0007121 regulates proliferation, migration, invasion, and epithelial–mesenchymal transition of trophoblast cells by miR-182-5p/PGF axis in preeclampsia |
| title_sort | circular rna hsa circ 0007121 regulates proliferation migration invasion and epithelial mesenchymal transition of trophoblast cells by mir 182 5p pgf axis in preeclampsia |
| topic | pe hsa_circ_0007121 mir-182-5p, pgf |
| url | https://doi.org/10.1515/med-2020-0230 |
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