Zebrafish Carrying <i>pycr1</i> Gene Deficiency Display Aging and Multiple Behavioral Abnormalities

Zebrafish Carrying <i>pycr1</i> Gene Deficiency Display Aging and Multiple Behavioral Abnormalities

Aging is a natural process that internal gene control and external stimuli mediate. Clinical data pointed out that homozygotic or heterozygotic mutation in the pyrroline-5-carboxylate reductase 1 (<i>PYCR1</i>) gene in humans caused cutis laxa (ARCL) disease, with progeroid appearance, l...

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Bibliographic Details
Main Authors: Sung-Tzu Liang, Gilbert Audira, Stevhen Juniardi, Jung-Ren Chen, Yu-Heng Lai, Zheng-Cai Du, Dar-Shong Lin, Chung-Der Hsiao
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
zebrafish
TALEN
PYCR1
aging
disease model
behavioral alteration
Online Access:https://www.mdpi.com/2073-4409/8/5/453

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