Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation

Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation

Here the authors report two structures of human PTH1R-Gs complex bound to ligands PTH and ABL, providing insight into the molecular mechanism of ligand duration.

Bibliographic Details
Main Authors: Xiuwen Zhai, Chunyou Mao, Qingya Shen, Shaokun Zang, Dan-Dan Shen, Huibing Zhang, Zhaohong Chen, Gang Wang, Changming Zhang, Yan Zhang, Zhihong Liu
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34009-x

Internet

https://doi.org/10.1038/s41467-022-34009-x

Similar Items