In vivo and in vitro anti-inflammatory and anti-nociceptive activities of lovastatin in rodents

In vivo and in vitro anti-inflammatory and anti-nociceptive activities of lovastatin in rodents

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Statins are among the most prescribed drugs in recent clinical practice. They are also known for their pleiotropic actions, which are independent of their lipid-lowering properties. The effect of lovastatin was investigated against carrageenan-induced paw edema in male Wistar rats (200-250 g) and on...

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Bibliographic Details
Main Authors: D.O. Gonçalves, I.B.F. Calou, R.P. Siqueira, A.A. Lopes, L.K.A. Leal, G.A.C. Brito, A.R. Tomé, G.S.B. Viana
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Statin
Inflammation
Anti-nociception
Myeloperoxidase
Cytokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000200011&lng=en&tlng=en

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