The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial
Statement of the Problem: Orthodontic removable appliances can facilitate the accumulation of certain microorganisms and microbial plaque on tooth surfaces and appliance components. Since long-term use of chemical agents is not recommended, an alternative option would be medicinal plants for disinfe...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2022-06-01
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| Series: | Journal of Dentistry |
| Subjects: | |
| Online Access: | https://dentjods.sums.ac.ir/article_48361_fa72a77206dd9c90fd6ba9b47432807e.pdf |
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| author | Navid Naseri Arefe Kalantari Khandani Tahereh Baherimoghadam Azade Kalantari Khandani Shahram Hamedani Sadegh Nouripour-Sisakht Roja Safaeian |
| author_facet | Navid Naseri Arefe Kalantari Khandani Tahereh Baherimoghadam Azade Kalantari Khandani Shahram Hamedani Sadegh Nouripour-Sisakht Roja Safaeian |
| author_sort | Navid Naseri |
| collection | DOAJ |
| description | Statement of the Problem: Orthodontic removable appliances can facilitate the accumulation of certain microorganisms and microbial plaque on tooth surfaces and appliance components. Since long-term use of chemical agents is not recommended, an alternative option would be medicinal plants for disinfection of the oral cavity.
Purpose: The aim of this study was to assess the efficacy of thymus vulgaris (T. vulgaris) essential oil to decrease the count of candida albicans (C. albicans) accumulated on removal orthodontic appliances
Materials and Method: In this 2-arm parallel controlled clinical trial, forty-four patients whose removable orthodontic appliances were contaminated with C. albicans were randomly divided into two groups by electronic random sampling. In the first group, T. vulgaris essential oil spray and in the second group, 0.2% chlorhexidine (CHX) spray was applied to the appliances. Thereafter, the C. albicans colony count was measured at baseline (T0) and at 2 (T1) and 5 (T2) days after the intervention. Microbial samples were collected by a sterile swab from 3 spots on the internal surface of orthodontic appliances. The Friedman test was used for within-group comparisons and the Mann Whitney test was employed to compare the efficacy of T. vulgaris essential oil with CHX.
Results: The results of this study revealed that continuous use of 2%T. vulgaris essential oil or 0.2% CHX significantly decreased the colony count of C. albicans on removable orthodontic appliances; Howevere, no significant difference was noted in the efficacy of 2% T. vulgaris essential oil and 0.2% CHX in decreasing the C. albicans colony count.
Conclusion: T. vulgaris essential oil and CHX have favorable antimicrobial activity against C. albicans. Moreover, 2% T. vulgaris essential oil can be considered as an alternative to 0.2% CHX to eliminate fungal contamination of orthodontic appliances.
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| first_indexed | 2024-04-12T13:45:26Z |
| format | Article |
| id | doaj.art-0d13d2c6c25d4283a122a73608388452 |
| institution | Directory Open Access Journal |
| issn | 2345-6485 2345-6418 |
| language | English |
| last_indexed | 2024-04-12T13:45:26Z |
| publishDate | 2022-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dentistry |
| spelling | doaj.art-0d13d2c6c25d4283a122a736083884522022-12-22T03:30:42ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182022-06-01Supplement-June-2022Supplement-June-202219019710.30476/DENTJODS.2021.89317.1404The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical TrialNavid Naseri 0Arefe Kalantari Khandani 1Tahereh Baherimoghadam 2Azade Kalantari Khandani 3Shahram Hamedani 4Sadegh Nouripour-Sisakht 5Roja Safaeian 6Dept. of Orthodontic, School of Dentistry, Shiraz Branch, Azad University, Shiraz, Iran. Dentist, School of Dentistry, Shiraz Branch, Azad University, Shiraz, Iran. Dept. of Orthodontic, School of Dentistry, Shiraz Branch, Azad University, Shiraz, Iran. PhD Student, Dept. of Drug and Food Control, School of Pharmacy, Kerman University of Medical Science, Kerman, Iran. Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.Dept. of Natural Resources and Environmental Engineering, School of Agriculture, Shiraz University, Shiraz, Iran. Statement of the Problem: Orthodontic removable appliances can facilitate the accumulation of certain microorganisms and microbial plaque on tooth surfaces and appliance components. Since long-term use of chemical agents is not recommended, an alternative option would be medicinal plants for disinfection of the oral cavity. Purpose: The aim of this study was to assess the efficacy of thymus vulgaris (T. vulgaris) essential oil to decrease the count of candida albicans (C. albicans) accumulated on removal orthodontic appliances Materials and Method: In this 2-arm parallel controlled clinical trial, forty-four patients whose removable orthodontic appliances were contaminated with C. albicans were randomly divided into two groups by electronic random sampling. In the first group, T. vulgaris essential oil spray and in the second group, 0.2% chlorhexidine (CHX) spray was applied to the appliances. Thereafter, the C. albicans colony count was measured at baseline (T0) and at 2 (T1) and 5 (T2) days after the intervention. Microbial samples were collected by a sterile swab from 3 spots on the internal surface of orthodontic appliances. The Friedman test was used for within-group comparisons and the Mann Whitney test was employed to compare the efficacy of T. vulgaris essential oil with CHX. Results: The results of this study revealed that continuous use of 2%T. vulgaris essential oil or 0.2% CHX significantly decreased the colony count of C. albicans on removable orthodontic appliances; Howevere, no significant difference was noted in the efficacy of 2% T. vulgaris essential oil and 0.2% CHX in decreasing the C. albicans colony count. Conclusion: T. vulgaris essential oil and CHX have favorable antimicrobial activity against C. albicans. Moreover, 2% T. vulgaris essential oil can be considered as an alternative to 0.2% CHX to eliminate fungal contamination of orthodontic appliances. https://dentjods.sums.ac.ir/article_48361_fa72a77206dd9c90fd6ba9b47432807e.pdforthodontic appliances; essential oil; candida albicans; chlorhexidine |
| spellingShingle | Navid Naseri Arefe Kalantari Khandani Tahereh Baherimoghadam Azade Kalantari Khandani Shahram Hamedani Sadegh Nouripour-Sisakht Roja Safaeian The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial Journal of Dentistry orthodontic appliances; essential oil; candida albicans; chlorhexidine |
| title | The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial |
| title_full | The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial |
| title_fullStr | The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial |
| title_full_unstemmed | The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial |
| title_short | The Effect of Thymus Vulgaris Essential Oil and Chlorhexidine on Candida Albicans Accumulated on Removable Orthodontic Appliance: A Clinical Trial |
| title_sort | effect of thymus vulgaris essential oil and chlorhexidine on candida albicans accumulated on removable orthodontic appliance a clinical trial |
| topic | orthodontic appliances; essential oil; candida albicans; chlorhexidine |
| url | https://dentjods.sums.ac.ir/article_48361_fa72a77206dd9c90fd6ba9b47432807e.pdf |
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