MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

Abstract Background Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and function, as evidenced by recent results demonstrating the impact of microexons on behaviour and cognition. H...

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Bibliographic Details
Main Authors: Guillermo E. Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo J. R. Fernandes, Veronika R. Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A. Miska, Martin Hemberg
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Biology
Subjects:
Microexons
Splicing
Alternative splicing
Neuronal development
Single-cell
Reproducible software
Online Access:https://doi.org/10.1186/s13059-020-02246-2

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