The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence.
Despite the advent of effective antiretroviral therapy (ART), human immunodeficiency virus (HIV) continues to pose major challenges, with extensive pathogenesis during acute and chronic infection prior to ART initiation and continued persistence in a reservoir of infected CD4 T cells during long-ter...
Main Authors: | Zachary Strongin, Timothy N Hoang, Gregory K Tharp, Andrew R Rahmberg, Justin L Harper, Kevin Nguyen, Lavinia Franchitti, Barbara Cervasi, Max Lee, Zhan Zhang, Eli A Boritz, Guido Silvestri, Vincent C Marconi, Steven E Bosinger, Jason M Brenchley, Deanna A Kulpa, Mirko Paiardini |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-07-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010723 |
Similar Items
-
PP 4.18 – 00213 Dynamics and antiviral role of TOX+ TCF1+ CD39+ CD8 T cells in lymphoid tissue of SIV-infected rhesus macaques
by: Z. Strongin, et al.
Published: (2022-12-01) -
Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.
by: Michelle Zanoni, et al.
Published: (2020-09-01) -
Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys
by: Joseph C. Mudd, et al.
Published: (2020-09-01) -
OP 4.8 – 00149 CD8+ T cells promote hiv latency in CD4+ T cells through the downmodulation of NF-kB
by: S. Mutascio, et al.
Published: (2022-12-01) -
Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
by: Simone Joas, et al.
Published: (2020-02-01)