Age changes of human serum polyreactive immunoglobulins (PRIG) activity
It has been determined that activity of serum polyreactive immunoglobulins (PRIG) changes with age in practically healthy people at the age from twenty five to seventy. Therewith, the activity of serum IgG PRIG increases most of all (about 3-4 times), while IgM PRIG activity, on the contrary, does n...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2014-10-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Bobrovnik_5_14.pdf |
| _version_ | 1797427755085725696 |
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| author | S. A. Bobrovnik M. A. Demchenko S. V. Komisarenko |
| author_facet | S. A. Bobrovnik M. A. Demchenko S. V. Komisarenko |
| author_sort | S. A. Bobrovnik |
| collection | DOAJ |
| description | It has been determined that activity of serum polyreactive immunoglobulins (PRIG) changes with age in practically healthy people at the age from twenty five to seventy. Therewith, the activity of serum IgG PRIG increases most of all (about 3-4 times), while IgM PRIG activity, on the contrary, does not increase, but sometimes even decreases with age. IgA PRIG activity varies significantly more than IgG PRIG activity and, besides, IgА PRIG significantly less depends on age than IgG PRIG. The age changes in the activity of human serum PRIG, belonging to different types of immunoglobulins, may evidence for the important functional role of these immunoglobulins that has to be clarified. |
| first_indexed | 2024-03-09T08:49:37Z |
| format | Article |
| id | doaj.art-0d1761ba60964979a5235990c0071ddd |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-09T08:49:37Z |
| publishDate | 2014-10-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-0d1761ba60964979a5235990c0071ddd2023-12-02T14:35:57ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032014-10-0186515115510.15407/ubj86.05.151Age changes of human serum polyreactive immunoglobulins (PRIG) activityS. A. Bobrovnik0M. A. Demchenko1S. V. Komisarenko2Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, KyivPalladin Institute of Biochemistry, National Academy of Sciences of Ukraine, KyivPalladin Institute of Biochemistry, National Academy of Sciences of Ukraine, KyivIt has been determined that activity of serum polyreactive immunoglobulins (PRIG) changes with age in practically healthy people at the age from twenty five to seventy. Therewith, the activity of serum IgG PRIG increases most of all (about 3-4 times), while IgM PRIG activity, on the contrary, does not increase, but sometimes even decreases with age. IgA PRIG activity varies significantly more than IgG PRIG activity and, besides, IgА PRIG significantly less depends on age than IgG PRIG. The age changes in the activity of human serum PRIG, belonging to different types of immunoglobulins, may evidence for the important functional role of these immunoglobulins that has to be clarified.http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Bobrovnik_5_14.pdfactivity of polyreactive IgGage changesELISA |
| spellingShingle | S. A. Bobrovnik M. A. Demchenko S. V. Komisarenko Age changes of human serum polyreactive immunoglobulins (PRIG) activity The Ukrainian Biochemical Journal activity of polyreactive IgG age changes ELISA |
| title | Age changes of human serum polyreactive immunoglobulins (PRIG) activity |
| title_full | Age changes of human serum polyreactive immunoglobulins (PRIG) activity |
| title_fullStr | Age changes of human serum polyreactive immunoglobulins (PRIG) activity |
| title_full_unstemmed | Age changes of human serum polyreactive immunoglobulins (PRIG) activity |
| title_short | Age changes of human serum polyreactive immunoglobulins (PRIG) activity |
| title_sort | age changes of human serum polyreactive immunoglobulins prig activity |
| topic | activity of polyreactive IgG age changes ELISA |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Bobrovnik_5_14.pdf |
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