Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020
Objective To estimate the incidence and describe the demographic characteristics of keratoconus (KC) in Colombia using national health registry data between January 1st 2015 and December 31th 2020.Methods and analysis We conducted a nationwide, population-based study using the Integrated Social Prot...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open Ophthalmology |
| Online Access: | https://bmjophth.bmj.com/content/8/1/e001238.full |
| _version_ | 1797367518079221760 |
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| author | William Rojas-Carabali Alejandra de-la-Torre Carlos Cifuentes-González Germán Mejia-Salgado Laura Zarate-Pinzón Luisa Fernanda Peña-Pulgar Diego Polania Danna Lesley Cruz-Reyes |
| author_facet | William Rojas-Carabali Alejandra de-la-Torre Carlos Cifuentes-González Germán Mejia-Salgado Laura Zarate-Pinzón Luisa Fernanda Peña-Pulgar Diego Polania Danna Lesley Cruz-Reyes |
| author_sort | William Rojas-Carabali |
| collection | DOAJ |
| description | Objective To estimate the incidence and describe the demographic characteristics of keratoconus (KC) in Colombia using national health registry data between January 1st 2015 and December 31th 2020.Methods and analysis We conducted a nationwide, population-based study using the Integrated Social Protection Information System from the Colombian Ministry of Health, the unique official database in the country. We used the International Classification of Diseases code for KC (H186) to identify the number of new cases of KC and estimate the incidence rates both overall and according to age and sex. We made a standard morbidity ratio map to graph Colombia’s morbidity risk of KC onset.Results Of 50 372 424 subjects, 21 710 had KC between 2015 and 2020. However, due to the COVID-19 pandemic, all the incidence rates of this study were based on the 18 419 reported until 2019. The incidence rate in the general population was 10.36 (95% CI 10.08 to 10.64) per 100 000 inhabitants. The incidence peak among males was in their early 20s and females in their late 20s. The overall male to female incidence rate ratio was 1.60. Regarding the distribution of the disease, most cases were reported in Bogotá (48.64%), Antioquia (14.04%) and Cundinamarca (10.38%).Conclusion We performed the first nationwide, population-based study of KC in Latin America, finding distribution patterns similar to those reported in the literature. This study provides valuable information on the epidemiology of KC in Colombia, which is helpful in the development of policies for the diagnosis, prevention and treatment of the disease. |
| first_indexed | 2024-03-08T17:18:30Z |
| format | Article |
| id | doaj.art-0d18ed5e3b174ed385206a1588c639bc |
| institution | Directory Open Access Journal |
| issn | 2397-3269 |
| language | English |
| last_indexed | 2024-03-08T17:18:30Z |
| publishDate | 2023-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Ophthalmology |
| spelling | doaj.art-0d18ed5e3b174ed385206a1588c639bc2024-01-03T08:30:06ZengBMJ Publishing GroupBMJ Open Ophthalmology2397-32692023-12-018110.1136/bmjophth-2023-001238Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020William Rojas-Carabali0Alejandra de-la-Torre1Carlos Cifuentes-González2Germán Mejia-Salgado3Laura Zarate-Pinzón4Luisa Fernanda Peña-Pulgar5Diego Polania6Danna Lesley Cruz-Reyes7Neuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaImmunology, Universidad Del Rosario Escuela de Medicina y Ciencias de la Salud, Bogotá, ColombiaNeuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaNeuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaNeuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaNeuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaNeuroscience Research Group (NEUROS), NeuroVitae Center. Institute of Translational Medicine (IMT). Escuela de Medicina y Ciencias de la Salud. Universidad del Rosario, Bogotá, ColombiaGrupo de Investigación Clínica, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, ColombiaObjective To estimate the incidence and describe the demographic characteristics of keratoconus (KC) in Colombia using national health registry data between January 1st 2015 and December 31th 2020.Methods and analysis We conducted a nationwide, population-based study using the Integrated Social Protection Information System from the Colombian Ministry of Health, the unique official database in the country. We used the International Classification of Diseases code for KC (H186) to identify the number of new cases of KC and estimate the incidence rates both overall and according to age and sex. We made a standard morbidity ratio map to graph Colombia’s morbidity risk of KC onset.Results Of 50 372 424 subjects, 21 710 had KC between 2015 and 2020. However, due to the COVID-19 pandemic, all the incidence rates of this study were based on the 18 419 reported until 2019. The incidence rate in the general population was 10.36 (95% CI 10.08 to 10.64) per 100 000 inhabitants. The incidence peak among males was in their early 20s and females in their late 20s. The overall male to female incidence rate ratio was 1.60. Regarding the distribution of the disease, most cases were reported in Bogotá (48.64%), Antioquia (14.04%) and Cundinamarca (10.38%).Conclusion We performed the first nationwide, population-based study of KC in Latin America, finding distribution patterns similar to those reported in the literature. This study provides valuable information on the epidemiology of KC in Colombia, which is helpful in the development of policies for the diagnosis, prevention and treatment of the disease.https://bmjophth.bmj.com/content/8/1/e001238.full |
| spellingShingle | William Rojas-Carabali Alejandra de-la-Torre Carlos Cifuentes-González Germán Mejia-Salgado Laura Zarate-Pinzón Luisa Fernanda Peña-Pulgar Diego Polania Danna Lesley Cruz-Reyes Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 BMJ Open Ophthalmology |
| title | Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| title_full | Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| title_fullStr | Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| title_full_unstemmed | Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| title_short | Colombian Ocular Diseases Epidemiology Study (CODES): incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| title_sort | colombian ocular diseases epidemiology study codes incidence and sociodemographic characterisation of keratoconus between 2015 and 2020 |
| url | https://bmjophth.bmj.com/content/8/1/e001238.full |
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