HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
Objective: To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia. Study Design: Cross sectional study. Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakista...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Army Medical College Rawalpindi
2018-12-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/2556/2094 |
| _version_ | 1818843604421967872 |
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| author | Amara Gul Javed Yousaf |
| author_facet | Amara Gul Javed Yousaf |
| author_sort | Amara Gul |
| collection | DOAJ |
| description | Objective:
To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia.
Study Design: Cross sectional study.
Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 to June 2017.
Material and Methods:
Fifty patients diagnosed with PDD at Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 until June 2017 and fifty healthy individuals participated in the study. Blood samples were examined for serum 25 hydroxy vitamin D. Following, Parkinson’s disease cognitive rating scale was administered to assess cortical and sub-cortical cognitive functioning.
Results:
Results showed that patients with PDD were deficient in serum 25 hydroxy vitamin D and cortical/subcortical cognitive functioning in contrast with healthy individuals. Serum 25 hydroxy Vitamin D and education level of patients with PDD were significant predictors of cortical and subcortical cognitive impairment.
Conclusion:
Hypovitaminosis D is a biomarker of cortical and subcortical cognitive deficits in patients with PDD. |
| first_indexed | 2024-12-19T05:00:31Z |
| format | Article |
| id | doaj.art-0d1bfdb7870a4600847ca8d3e1e3b340 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-19T05:00:31Z |
| publishDate | 2018-12-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-0d1bfdb7870a4600847ca8d3e1e3b3402022-12-21T20:35:07ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422018-12-0168616051608HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIAAmara Gul0Javed Yousaf1The Islamia University of Bahawalpur PakistanThe Islamia University of Bahawalpur PakistanObjective: To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia. Study Design: Cross sectional study. Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 to June 2017. Material and Methods: Fifty patients diagnosed with PDD at Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 until June 2017 and fifty healthy individuals participated in the study. Blood samples were examined for serum 25 hydroxy vitamin D. Following, Parkinson’s disease cognitive rating scale was administered to assess cortical and sub-cortical cognitive functioning. Results: Results showed that patients with PDD were deficient in serum 25 hydroxy vitamin D and cortical/subcortical cognitive functioning in contrast with healthy individuals. Serum 25 hydroxy Vitamin D and education level of patients with PDD were significant predictors of cortical and subcortical cognitive impairment. Conclusion: Hypovitaminosis D is a biomarker of cortical and subcortical cognitive deficits in patients with PDD.https://www.pafmj.org/index.php/PAFMJ/article/view/2556/2094vitamin ddementiacognition |
| spellingShingle | Amara Gul Javed Yousaf HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA Pakistan Armed Forces Medical Journal vitamin d dementia cognition |
| title | HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA |
| title_full | HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA |
| title_fullStr | HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA |
| title_full_unstemmed | HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA |
| title_short | HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA |
| title_sort | hypovitaminosis d cortical and sub cortical cognitive functioning deficts in patients with parkinson s disease dementia |
| topic | vitamin d dementia cognition |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/2556/2094 |
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