Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.
Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment.. Methods: We did an observational prospective study, after acquiring ethical review le...
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| Format: | Article |
| Language: | English |
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KARACHI MEDICAL AND DENTAL COLLEGE
2024-02-01
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| Series: | Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College |
| Subjects: | |
| Online Access: | https://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/791 |
| _version_ | 1797289372192604160 |
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| author | Mohammad Ishaq Syeda Urooj Riaz Nousheen Iqbal Asad Raza Jafri Urooj Fatima Amir Hussain Khizra Ishaq Shifa Ishaq |
| author_facet | Mohammad Ishaq Syeda Urooj Riaz Nousheen Iqbal Asad Raza Jafri Urooj Fatima Amir Hussain Khizra Ishaq Shifa Ishaq |
| author_sort | Mohammad Ishaq |
| collection | DOAJ |
| description |
Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment..
Methods: We did an observational prospective study, after acquiring ethical review letter from IRB Medicine department outpatient services of Jinnah Medical College Hospital Korangi was used where patients with Uveitis were referred for evaluation of systemic disease during jan 2019 to dec 2020. These patients underwent history, examination and biochemical and radiological investigations and were followed over a period of 1 year to see response to treatment.
Results: A total of 372 patients presented with established uveitis out of which 36 patients i.e. 66 eyes presented to our eye clinic with decrease in vision with a mean age of 42±2 years. Among 36 patients, 89% presented with redness of eye and 72% presented with eye pain where as 8 % pre- sented with photophobia and floaters. Biochemically >10mg/dl calcium was observed in 18(50%) pa- tients and ACE level was found to be more than 40nmol/ml/min in 30(83.3%) patients. Among them 32 (88.9%) patients showed resolved inflammation whereas 2(5.56%) showed a change in inflamma- tion and 2(5.56%) showed no change.
Conclusion: We found sarcoid uveitis as fairly common cause of uveitis. The patients were treated with the standard treatment of steroids and immunosuppressants i.e. Azathioprine and we concluded that use of steroids and immunosuppressant improved the outcome in our patients. The patients re- sponded fairly well to the designed treatment.
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| first_indexed | 2024-03-07T19:04:00Z |
| format | Article |
| id | doaj.art-0d1cc71622b347d880dd58216629a257 |
| institution | Directory Open Access Journal |
| issn | 1563-3241 |
| language | English |
| last_indexed | 2024-03-07T19:04:00Z |
| publishDate | 2024-02-01 |
| publisher | KARACHI MEDICAL AND DENTAL COLLEGE |
| record_format | Article |
| series | Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College |
| spelling | doaj.art-0d1cc71622b347d880dd58216629a2572024-03-01T09:44:48ZengKARACHI MEDICAL AND DENTAL COLLEGEAnnals of Abbasi Shaheed Hospital and Karachi Medical & Dental College1563-32412024-02-01291Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.Mohammad Ishaq0Syeda Urooj Riaz1Nousheen Iqbal2Asad Raza Jafri3Urooj Fatima4Amir Hussain5Khizra Ishaq6Shifa Ishaq7Department of Medicine, Jinnah Medical College HospitalDepartment of Medicine, Jinnah Medical College HospitalDepartment of Medicine, Jinnah Medical College HospitalDepartment of Ophthalamology, Jinnah Medical College Hospital Department of Anatomy, Jinnah Medical College HospitalDepartment of Ophthalamology, Jinnah Medical College Hospital Department of Ophthalamology, Jinnah Medical College Hospital Department of Ophthalamology, Jinnah Medical College Hospital Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment.. Methods: We did an observational prospective study, after acquiring ethical review letter from IRB Medicine department outpatient services of Jinnah Medical College Hospital Korangi was used where patients with Uveitis were referred for evaluation of systemic disease during jan 2019 to dec 2020. These patients underwent history, examination and biochemical and radiological investigations and were followed over a period of 1 year to see response to treatment. Results: A total of 372 patients presented with established uveitis out of which 36 patients i.e. 66 eyes presented to our eye clinic with decrease in vision with a mean age of 42±2 years. Among 36 patients, 89% presented with redness of eye and 72% presented with eye pain where as 8 % pre- sented with photophobia and floaters. Biochemically >10mg/dl calcium was observed in 18(50%) pa- tients and ACE level was found to be more than 40nmol/ml/min in 30(83.3%) patients. Among them 32 (88.9%) patients showed resolved inflammation whereas 2(5.56%) showed a change in inflamma- tion and 2(5.56%) showed no change. Conclusion: We found sarcoid uveitis as fairly common cause of uveitis. The patients were treated with the standard treatment of steroids and immunosuppressants i.e. Azathioprine and we concluded that use of steroids and immunosuppressant improved the outcome in our patients. The patients re- sponded fairly well to the designed treatment. https://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/791SarcoidosisUveitisSun ClassificationVisual AcquitySystemic Diseases |
| spellingShingle | Mohammad Ishaq Syeda Urooj Riaz Nousheen Iqbal Asad Raza Jafri Urooj Fatima Amir Hussain Khizra Ishaq Shifa Ishaq Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College Sarcoidosis Uveitis Sun Classification Visual Acquity Systemic Diseases |
| title | Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. |
| title_full | Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. |
| title_fullStr | Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. |
| title_full_unstemmed | Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. |
| title_short | Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan. |
| title_sort | sarcoid uveitis an experience from a tertiary care hospital in pakistan |
| topic | Sarcoidosis Uveitis Sun Classification Visual Acquity Systemic Diseases |
| url | https://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/791 |
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