Spinal cord injury causes chronic bone marrow failure
Spinal cord injury (SCI) often leads to immune dysfunction, but mechanistic insights are still lacking. Here the authors show that SCI alters chemokine signaling and induces long, persisting defects in hematopoietic stem and progenitor cell migration, thereby entrapping them in the bone marrow and d...
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Bibliographic Details
| Main Authors: |
Randall S. Carpenter,
Jessica M. Marbourg,
Faith H. Brennan,
Katherine A. Mifflin,
Jodie C. E. Hall,
Roselyn R. Jiang,
Xiaokui M. Mo,
Malith Karunasiri,
Matthew H. Burke,
Adrienne M. Dorrance,
Phillip G. Popovich |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17564-z
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