The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19
Introduction: COVID-19 disease caused by the SARS-Cov-2 virus is characterized by clinical spectra of varying severity. Coagulopathy and inflammation are the most important factors associated with COVID-19 severity. The use of a biomarker of inflammation and coagulation factors has not yet been clar...
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| Format: | Article |
| Language: | English |
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SERNEV
2022-12-01
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| Series: | Family Practice and Palliative Care |
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| Online Access: | https://dergipark.org.tr/en/download/article-file/2491949 |
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| author | Ayşe Alga Batırel Sevtap Acer Nilüfer Zorlutuna Kaymak Gizem Dogan Gokce Mehmet Tezcan Nesrin Şen |
| author_facet | Ayşe Alga Batırel Sevtap Acer Nilüfer Zorlutuna Kaymak Gizem Dogan Gokce Mehmet Tezcan Nesrin Şen |
| author_sort | Ayşe Alga Batırel |
| collection | DOAJ |
| description | Introduction: COVID-19 disease caused by the SARS-Cov-2 virus is characterized by clinical spectra of varying severity. Coagulopathy and inflammation are the most important factors associated with COVID-19 severity. The use of a biomarker of inflammation and coagulation factors has not yet been clarified. The present study aimed to examine the role of CRP/Albumin, an inflammation marker, in predicting the course of COVID-19 disease.Methods: The Demographic, laboratory, and prognosis of 457 patients who were hospitalized during the COVID-19 pandemic service between April and May 2020 were analyzed retrospectively. The relationship between the patients' CRP/Albumin ratio and disease severity, length of hospital stays, and prognosis were analyzed.Results: The rate of hospitalization in the intensive care unit was 10.5% (n=48), mechanical ventilation was 8.1% (n=37), and death was 1.3% (n=6). The CRP/albumin ratio was statistically higher in those with lung infiltration (p=0.005), those who were taken to the intensive care unit (p lt;0.001), and those who needed mechanical ventilation (p lt;0.001). A positive significant correlation was found between the length of hospital stay and the CRP/albumin ratio(r=0.412, p lt; 0.001).Conclusion: The CRP/Albumin ratio is thought to be an auxiliary marker for doctors in the early transfer of patients to the intensive care unit, the early detection of those in need of MV, and the determination of lung infiltration.Keywords: COVID-19, CRP/albumin ratio, prognosis |
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| format | Article |
| id | doaj.art-0d1ebdea4c954996a34dbec4ed61e2cf |
| institution | Directory Open Access Journal |
| issn | 2459-1505 |
| language | English |
| last_indexed | 2025-02-18T08:10:00Z |
| publishDate | 2022-12-01 |
| publisher | SERNEV |
| record_format | Article |
| series | Family Practice and Palliative Care |
| spelling | doaj.art-0d1ebdea4c954996a34dbec4ed61e2cf2024-11-04T07:54:17ZengSERNEVFamily Practice and Palliative Care2459-15052022-12-017513213610.22391/fppc.1132063544The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19Ayşe Alga Batırel0https://orcid.org/0000-0002-6005-636XSevtap Acer1https://orcid.org/0000-0002-4805-0555Nilüfer Zorlutuna Kaymak2https://orcid.org/0000-0002-9673-824XGizem Dogan Gokce3https://orcid.org/0000-0003-1328-7103Mehmet Tezcan4https://orcid.org/0000-0002-1753-4936Nesrin Şen5https://orcid.org/0000-0003-0966-0075Department of Infectious and Clinical Microbiology Diseases, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulDepartment of Rheumatology, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulDepartment of Ophthalmology, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulDepartment of Ophthalmology, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulDepartment of Rheumatology, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulDepartment of Rheumatology, Kartal Dr Lutfi Kirdar City Hospital, University of Health Sciences, IstanbulIntroduction: COVID-19 disease caused by the SARS-Cov-2 virus is characterized by clinical spectra of varying severity. Coagulopathy and inflammation are the most important factors associated with COVID-19 severity. The use of a biomarker of inflammation and coagulation factors has not yet been clarified. The present study aimed to examine the role of CRP/Albumin, an inflammation marker, in predicting the course of COVID-19 disease.Methods: The Demographic, laboratory, and prognosis of 457 patients who were hospitalized during the COVID-19 pandemic service between April and May 2020 were analyzed retrospectively. The relationship between the patients' CRP/Albumin ratio and disease severity, length of hospital stays, and prognosis were analyzed.Results: The rate of hospitalization in the intensive care unit was 10.5% (n=48), mechanical ventilation was 8.1% (n=37), and death was 1.3% (n=6). The CRP/albumin ratio was statistically higher in those with lung infiltration (p=0.005), those who were taken to the intensive care unit (p lt;0.001), and those who needed mechanical ventilation (p lt;0.001). A positive significant correlation was found between the length of hospital stay and the CRP/albumin ratio(r=0.412, p lt; 0.001).Conclusion: The CRP/Albumin ratio is thought to be an auxiliary marker for doctors in the early transfer of patients to the intensive care unit, the early detection of those in need of MV, and the determination of lung infiltration.Keywords: COVID-19, CRP/albumin ratio, prognosishttps://dergipark.org.tr/en/download/article-file/2491949covid-19crp/albumin oranıprognozcovid-19crp/albumin ratioprognosis |
| spellingShingle | Ayşe Alga Batırel Sevtap Acer Nilüfer Zorlutuna Kaymak Gizem Dogan Gokce Mehmet Tezcan Nesrin Şen The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 Family Practice and Palliative Care covid-19 crp/albumin oranı prognoz covid-19 crp/albumin ratio prognosis |
| title | The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 |
| title_full | The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 |
| title_fullStr | The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 |
| title_full_unstemmed | The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 |
| title_short | The effect of CRP/albumin ratio on prognosis of hospitalized patients due to COVID-19 |
| title_sort | effect of crp albumin ratio on prognosis of hospitalized patients due to covid 19 |
| topic | covid-19 crp/albumin oranı prognoz covid-19 crp/albumin ratio prognosis |
| url | https://dergipark.org.tr/en/download/article-file/2491949 |
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