Immunogenic self-peptides - the great unknowns in autoimmunity: Identifying T-cell epitopes driving the autoimmune response in autoimmune diseases

HLA-associated autoimmune diseases likely arise from T-cell-mediated autoimmune responses against certain self-peptides from the broad HLA-presented immunopeptidomes. The limited knowledge of the autoimmune target peptides has so far compromised the basic understanding of autoimmune pathogenesis. Th...

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Détails bibliographiques
Auteur principal: Jörg Christoph Prinz
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2023-01-01
Collection:Frontiers in Immunology
Sujets:
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1097871/full