Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes
<b>AIM:</b> To describe and compare the corneal endothelial cell density and morphology in young, low and moderate myopic Chinese adults in Malaysian Chinese population.<b>METHODS:</b> Non-contact specular microscopy (Topcon SP3000P, Tokyo, Japan) was performed in low (<i&...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2013-08-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.cn/en_publish/2013/4/20130411.pdf |
| _version_ | 1818530004661698560 |
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| author | Jane Mei Chun Samaneh Delshad |
| author_facet | Jane Mei Chun Samaneh Delshad |
| author_sort | Jane Mei Chun |
| collection | DOAJ |
| description | <b>AIM:</b> To describe and compare the corneal endothelial cell density and morphology in young, low and moderate myopic Chinese adults in Malaysian Chinese population.<b>METHODS:</b> Non-contact specular microscopy (Topcon SP3000P, Tokyo, Japan) was performed in low (<i>n</i>=78; 21.22±1.51 years) and moderate (<i>n</i>=78; 21.82±1.40 years) myopic subjects. The mean of three consecutive measurements of endothelial cell density (MCD), coefficient of variation (CV) in the cell size, and hexagonal appearance of the cell were obtained.<b>RESULTS:</b> In low myopic eyes the MCD was 3 063.0±176.2/mm<sup>2</sup>, the mean CV was 33.4±4.0% and the mean hexagonal appearance of the cell was 57.9±2.7%. In moderate myopic eyes the MCD was 2961.6±159.0/mm<sup>2</sup>, the mean CV was 33.9±3.6% and mean hexagonal appearance of the cell was 56.2±4.7%. There were statistically significant differences in MCD (<i>P</i><0.000) and hexagonal appearance of the cell (<i>P</i><0.005) between low and moderate myopic eyes.<b>CONCLUSION:</b>The corneal endothelial cell layer in more myopic eyes tends to have less MCD and cell hexagonality compared to lower myopic eyes. Nevertheless, there is no significant difference in CV between low and moderate myopic eyes. |
| first_indexed | 2024-12-11T17:14:14Z |
| format | Article |
| id | doaj.art-0d21e6d86a8547eb800e193cdf6c1da3 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-11T17:14:14Z |
| publishDate | 2013-08-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-0d21e6d86a8547eb800e193cdf6c1da32022-12-22T00:57:25ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982013-08-016446747010.3980/j.issn.2222-3959.2013.04.11Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyesJane Mei ChunSamaneh Delshad<b>AIM:</b> To describe and compare the corneal endothelial cell density and morphology in young, low and moderate myopic Chinese adults in Malaysian Chinese population.<b>METHODS:</b> Non-contact specular microscopy (Topcon SP3000P, Tokyo, Japan) was performed in low (<i>n</i>=78; 21.22±1.51 years) and moderate (<i>n</i>=78; 21.82±1.40 years) myopic subjects. The mean of three consecutive measurements of endothelial cell density (MCD), coefficient of variation (CV) in the cell size, and hexagonal appearance of the cell were obtained.<b>RESULTS:</b> In low myopic eyes the MCD was 3 063.0±176.2/mm<sup>2</sup>, the mean CV was 33.4±4.0% and the mean hexagonal appearance of the cell was 57.9±2.7%. In moderate myopic eyes the MCD was 2961.6±159.0/mm<sup>2</sup>, the mean CV was 33.9±3.6% and mean hexagonal appearance of the cell was 56.2±4.7%. There were statistically significant differences in MCD (<i>P</i><0.000) and hexagonal appearance of the cell (<i>P</i><0.005) between low and moderate myopic eyes.<b>CONCLUSION:</b>The corneal endothelial cell layer in more myopic eyes tends to have less MCD and cell hexagonality compared to lower myopic eyes. Nevertheless, there is no significant difference in CV between low and moderate myopic eyes.http://www.ijo.cn/en_publish/2013/4/20130411.pdfcorneamyopic eyesspecular microscopyendothelial cell densitymorphology |
| spellingShingle | Jane Mei Chun Samaneh Delshad Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes International Journal of Ophthalmology cornea myopic eyes specular microscopy endothelial cell density morphology |
| title | Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes |
| title_full | Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes |
| title_fullStr | Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes |
| title_full_unstemmed | Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes |
| title_short | Corneal endothelial cell density and morphology in low and moderate myopic Chinese eyes |
| title_sort | corneal endothelial cell density and morphology in low and moderate myopic chinese eyes |
| topic | cornea myopic eyes specular microscopy endothelial cell density morphology |
| url | http://www.ijo.cn/en_publish/2013/4/20130411.pdf |
| work_keys_str_mv | AT janemeichun cornealendothelialcelldensityandmorphologyinlowandmoderatemyopicchineseeyes AT samanehdelshad cornealendothelialcelldensityandmorphologyinlowandmoderatemyopicchineseeyes |