CYFIP2 serves as a prognostic biomarker and correlates with tumor immune microenvironment in human cancers

CYFIP2 serves as a prognostic biomarker and correlates with tumor immune microenvironment in human cancers

Abstract Background The mechanisms whereby CYFIP2 acts in tumor development and drives immune infiltration have been poorly explored. Thus, this study aimed to identifying the role of CYFIP2 in tumors and immune response. Methods In this study, we first explored expression patterns, diagnostic role...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Qiliang Peng, Bixin Ren, Kedao Xin, Weihui Liu, Md Shahin Alam, Yinyin Yang, Xuhao Gu, Yaqun Zhu, Ye Tian
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	BMC 2023-09-01
Σειρά:	European Journal of Medical Research
Θέματα:	CYFIP2 Immuno-oncology Biomarker Prognosis
Διαθέσιμο Online:	https://doi.org/10.1186/s40001-023-01366-2

Παρόμοια τεκμήρια

Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia
ανά: Xianhui Peng, κ.ά.
Έκδοση: (2024-01-01)

Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus
ανά: Yinhua Zhang, κ.ά.
Έκδοση: (2019-11-01)

The Downregulation of Prognosis- and Immune Infiltration-Related Gene CYFIP2 Serves as a Novel Target in ccRCC
ανά: Tong J, κ.ά.
Έκδοση: (2021-10-01)

CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target
ανά: Cong Xiao, κ.ά.
Έκδοση: (2024-12-01)

Elucidating the role of CYFIP2 in conferring cisplatin resistance in esophageal squamous cell carcinoma
ανά: Peipei Zhang, κ.ά.
Έκδοση: (2024-11-01)

Identification of CYFIP2 Arg87Cys Ligands via In Silico and In Vitro Approaches
ανά: Ísis Venturi Biembengut, κ.ά.
Έκδοση: (2024-02-01)

Identification of SHCBP1 as a potential biomarker involving diagnosis, prognosis, and tumor immune microenvironment across multiple cancers
ανά: Ning Wang, κ.ά.
Έκδοση: (2022-01-01)

Cyfip1 Regulates SynGAP1 at Hippocampal Synapses
ανά: Abhishek Sahasrabudhe, κ.ά.
Έκδοση: (2021-02-01)

CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
ανά: Barbara eBardoni, κ.ά.
Έκδοση: (2014-03-01)

New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes
ανά: Sabiha Abekhoukh, κ.ά.
Έκδοση: (2017-04-01)

Analysis and Experimental Validation of Rheumatoid Arthritis Innate Immunity Gene CYFIP2 and Pan-Cancer
ανά: ZhenYu Zhao, κ.ά.
Έκδοση: (2022-07-01)

Differential Role of the RAC1-Binding Proteins FAM49b (CYRI-B) and CYFIP1 in Platelets
ανά: Dmitri Sisario, κ.ά.
Έκδοση: (2024-02-01)

Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice
ανά: Yinhua Zhang, κ.ά.
Έκδοση: (2020-10-01)

CYFIP1 coordinate with RNMT to induce osteosarcoma cuproptosis via AURKAIP1 m7G modification
ανά: Zili Lin, κ.ά.
Έκδοση: (2025-02-01)

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice
ανά: Yinhua Zhang, κ.ά.
Έκδοση: (2019-01-01)

Overexpression of the autism candidate gene Cyfip1 pathologically enhances olivo-cerebellar signaling in mice
ανά: Silas E. Busch, κ.ά.
Έκδοση: (2023-07-01)

Cell-autonomous reduction of CYFIP2 changes dendrite length, dendritic protrusion morphology, and inhibitory synapse density in the hippocampal CA1 pyramidal neurons of 17-month-old mice
ανά: Yoonhee Kim, κ.ά.
Έκδοση: (2024-12-01)

CYFIP1 gene expression in umbilical cord blood and its relationship with maternal body mass index
ανά: Mahsa Eskandari, κ.ά.
Έκδοση: (2024-03-01)

circCYFIP2 Acts as a Sponge of miR-1205 and Affects the Expression of Its Target Gene E2F1 to Regulate Gastric Cancer Metastasis
ανά: Jing Lin, κ.ά.
Έκδοση: (2020-09-01)

Cell-autonomous reduction of CYFIP2 is insufficient to induce Alzheimer's disease-like pathologies in the hippocampal CA1 pyramidal neurons of aged mice
ανά: Ruiying Ma, κ.ά.
Έκδοση: (2023-12-01)

ELK3-CYFIP2 axis-mediated actin remodeling modulates metastasis and natural killer cell responses in triple-negative breast cancer
ανά: Seung Hee Choi, κ.ά.
Έκδοση: (2025-02-01)

Circulating biomarkers in the diagnosis and prognosis of immune checkpoint inhibitor-related myocarditis: time for a risk-based approach
ανά: Gillian Murtagh, κ.ά.
Έκδοση: (2024-02-01)

A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials
ανά: Jeffrey R. Whiteaker, κ.ά.
Έκδοση: (2023-05-01)

The role of biomarkers in personalized immunotherapy
ανά: Kamya Sankar, κ.ά.
Έκδοση: (2022-05-01)

Biomarker implication of kallikrein-related peptidases as prognostic tissue substrates of poor survival in colorectal cancer
ανά: Qiliang Peng, κ.ά.
Έκδοση: (2020-06-01)

Characterising CD8+ T cell transcriptomic and clonal consequences of immune checkpoint blockade for the treatment of cancer
ανά: Watson, RA
Έκδοση: (2023)

Editorial: Tumor microenvironment complexity and its therapeutic implications
ανά: Denner Santos dos Anjos, κ.ά.
Έκδοση: (2025-01-01)

Next generation immuno-oncology tumor profiling using a rapid, non-invasive, computational biophysics biomarker in early-stage breast cancer
ανά: Daniel Cook, κ.ά.
Έκδοση: (2023-04-01)

Potential Impact of IMbrave150 Results in the Evolving Treatment Landscape of Advanced Hepatocellular Carcinoma: A Multidisciplinary Expert Opinion
ανά: Kulik L, κ.ά.
Έκδοση: (2020-12-01)

Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment
ανά: Emily B. Harrison, κ.ά.
Έκδοση: (2018-04-01)

A bispecific anti-PD-1 and PD-L1 antibody induces PD-1 cleavage and provides enhanced anti-tumor activity
ανά: Diana I. Albu, κ.ά.
Έκδοση: (2024-12-01)

Germline genetic host factors as predictive biomarkers in immuno-oncology
ανά: Vylyny Chat, κ.ά.
Έκδοση: (2019-09-01)

Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations
ανά: Madyson Colton, κ.ά.
Έκδοση: (2020-11-01)

TEADs serve as potential prognostic biomarkers and targets for human gastric cancer
ανά: Meng-huan Wang, κ.ά.
Έκδοση: (2022-06-01)

Immunology of Cell Death in Cancer Immunotherapy
ανά: Lorenzo Galluzzi, κ.ά.
Έκδοση: (2021-05-01)

Editorial: Modulation of human immune parameters by anticancer therapies, volume II
ανά: Il-Kang Na, κ.ά.
Έκδοση: (2023-07-01)

A review of spatial profiling technologies for characterizing the tumor microenvironment in immuno-oncology
ανά: Bian Hu, κ.ά.
Έκδοση: (2022-10-01)

The role of LARP1 in communication between ovarian tumours and their immune microenvironment
ανά: Gross, F
Έκδοση: (2022)

Inflammatory response-based prognostication and personalized therapy decisions in clear cell renal cell cancer to aid precision oncology
ανά: Weimin Zhong, κ.ά.
Έκδοση: (2023-10-01)

Immuno-oncological treatment of Non-Small-Cell Lung Cancer (NSCLC) in advanced stage with Nivolumab
ανά: Fabio Venturella, κ.ά.
Έκδοση: (2023-03-01)