C-EBPβ mediates in cigarette/IL-17A-induced bronchial epithelial–mesenchymal transition in COPD mice

C-EBPβ mediates in cigarette/IL-17A-induced bronchial epithelial–mesenchymal transition in COPD mice

Abstract Background Cigarettes smoking and IL-17A contribute to chronic obstructive pulmonary disease (COPD), and have synergistical effect on bronchial epithelial cell proliferation. CCAAT/enhancer-binding protein β (C-EBPβ) could be induced by IL-17A and is up-regulated in COPD. We explored the ef...

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Bibliographic Details
Main Authors: Shuyuan Chu, Libing Ma, Yashan Wu, Xiaoli Zhao, Bo Xiao, Qilu Pan
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Pulmonary Medicine
Online Access:https://doi.org/10.1186/s12890-021-01738-6

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