Elevated Numbers of HIV-Specific Poly-Functional CD8+ T Cells With Stem Cell-Like and Follicular Homing Phenotypes in HIV-Exposed Seronegative Individuals

Elevated Numbers of HIV-Specific Poly-Functional CD8+ T Cells With Stem Cell-Like and Follicular Homing Phenotypes in HIV-Exposed Seronegative Individuals

HIV-specific CD8+ T cells are known to play a key role in viral control during acute and chronic HIV infection. Although many studies have demonstrated the importance of HIV-specific CD8+ T cells in viral control, its correlation with protection against HIV infection remains incompletely understood....

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Bibliographic Details
Main Authors: Sivasankaran Munusamy Ponnan, Kannan Thiruvengadam, Sujitha Kathirvel, Janani Shankar, Akshaya Rajaraman, Manikannan Mathaiyan, Thongadi Ramesh Dinesha, Selvamuthu Poongulali, Shanmugam Saravanan, Kailapuri Gangatharan Murugavel, Soumya Swaminathan, Srikanth Prasad Tripathy, Ujjwal Neogi, Vijayakumar Velu, Luke Elizabeth Hanna
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
HIV
HESN
ART
CTL
CXCR5+ CD8+
TSCM cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.638144/full

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