SINGLE DOMAIN ANTIBODIES AND BIOENGINEERING DRUGS ON THEIR BASIS: NEW OPPORTUNITIES FOR DIAGNOSTICS AND THERAPY

SINGLE DOMAIN ANTIBODIES AND BIOENGINEERING DRUGS ON THEIR BASIS: NEW OPPORTUNITIES FOR DIAGNOSTICS AND THERAPY

Almost 20 years ago, a unique class of antibodies devoid of L chains was discovered in Camelidae blood serum. Only one variable domain is responsible for antigen recognition in these unusual antibodies. A recombinant protein, which is analogue to such antigen-recognizing variable domain was called t...

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Bibliographic Details
Main Authors: E. N. Gorshkova, E. A. Vasilenko, S. V. Tillib, I. V. Astrakhantseva
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2016-12-01
Series:Медицинская иммунология
Subjects:
single-domain antibodies
сamel antibodies
nanoantibodies
vhh
bi-specific antibodies
bioengineered drugs
Online Access:https://www.mimmun.ru/mimmun/article/view/1131

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