Risk of mortality among inpatients with COVID‐19 and type 2 diabetes: National data from Kuwait

Abstract Introduction To investigate type 2 diabetes as a risk factor for COVID‐19 death following hospital admission in Kuwait. Methods A retrospective cohort study using data from a central hospital that cared for all hospitalized COVID‐19 patients in Kuwait. We investigated the association betwee...

Full description

Bibliographic Details
Main Authors: Ebaa Al‐Ozairi, Rosemary Brown, Yasmine Hamdan, Lulwa Alabdullah, Nia Voase, Jumana Al Kandari, Dalal Alsaeed, Abdulla Al Ozairi, Amal Hasan, Fahd Al‐Mulla, Srinivasa Vittal Katikireddi, Stuart R. Gray, Jason M. R. Gill, Carlos A. Celis‐Morales, Naveed Sattar, Paul Welsh
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Endocrinology, Diabetes & Metabolism
Subjects:
Online Access:https://doi.org/10.1002/edm2.287
Description
Summary:Abstract Introduction To investigate type 2 diabetes as a risk factor for COVID‐19 death following hospital admission in Kuwait. Methods A retrospective cohort study using data from a central hospital that cared for all hospitalized COVID‐19 patients in Kuwait. We investigated the association between type 2 diabetes, with COVID‐19 mortality using multiply imputed logistic regression and calculated the population attributable fraction. Results A total of 5333 patients were admitted with COVID‐19, of whom 244 died (4.6%). Diabetes prevalence was 24.8%, but 53.7% of those who died had diabetes. After adjusting for age, sex, ethnicity and other comorbidities, diabetes was associated with death (OR 1.70 [95% CI 1.23, 2.34]) and admission to the intensive care unit more than 3 days after initial admission (OR 1.78 [95% CI 1.17, 2.70]). Assuming causality, the population attributable fraction for type 2 diabetes in COVID‐19 death was 19.6% (95% CI 10.8, 35.6). Conclusion Type 2 diabetes is a strong risk factor for COVID‐19 death in the Middle East. Given the high prevalence of type 2 diabetes in the Middle East, as well as many Western countries, the public health implications are considerable.
ISSN:2398-9238